Product apis-tgf-beta-smad

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Catalog	name	Description	price
R-C-2624	Adaphostin CAS:241127-58-2	Adaphostin is a novel activator of Fas-mediated death pathway in Bcr/Abl-positive leukaemia.	price>
R-C-2625	FR 236924 CAS:28399-31-7	Selective PKCεactivator that displays>7-fold selectivity over other PKC isozymes.Stimulates glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo.	price>
R-C-2626	SC-9 cas:102649-78-5	SC-9 is a protein kinase C(PKC)activator in the presence of Ca2+.	price>
R-C-2627	PD 180970 CAS:287204-45-9	PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8nM and 50nM, respectively.	price>
R-C-2628	Narciclasine CAS:29477-83-6	Narciclasine is a plant growth modulator.Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway,greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.	price>
R-C-2629	Chelerythrine CAS: 34316-15-9	Chelerythrine is a natural alkaloid,acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist,with an IC50 of 0.7μM.Chelerythrine has antitumor,antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5μM and displaces Bax from BclXL.Chelerythrine triggers apoptosis and autophagy.	price>
R-C-2631	Sotrastaurin (AEB071) CAS:425637-18-9	Sotrastaurin(AEB071)is a potent and orally-active pan-PKC inhibitor,with Kis of 0.22 nM,0.64nM,0.95nM,1.8nM,2.1nM and 3.2nM for PKCθ,PKCβ,PKCα,PKCη,PKCδ and PKCε,respectively.	price>
R-C-2632	RepSox (E-616452) CAS:446859-33-2	RepSox(E-616452)is a potent and selective of the TGFβR-1/ALK5 inhibitor which inhibits ALK5 autophosphorylation with an IC50 of 4nM.	price>
R-C-2633	Epicatechin CAS:490-46-0	Epicatechin is a flavan-3-ol,a type of natural phenol and antioxidant.It is a plant secondary metabolite.The name of the catechin chemical family derives from catechu,which is the tannic juice or boiled extract of Mimosa catechu (Acacia catechu L.f).	price>
R-C-2634	Dequalinium Chloride CAS:522-51-0	Dequalinium chloride is a topical bacteriostat that is available as various salts.It is used in wound dressings and mouth infections and may also have antifungal action,but may cause skin ulceration.	price>

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