Product apis-metabolism

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Catalog	name	Description	price
R-C-2764	Pralatrexate (NSC 754230) CAS：146464-95-1	Pralatrexate(NSC 754230)is an antifolate, and structurally a folate analog.Its IC50 is<300nM in some cell lines.Pralatrexate induces tumor cell apoptosis.	price>
R-C-2765	Pitavastatin(NK-104) CAS:147526-32-7	Pitavastatin Calcium(NK-104,P-872441,itavastatin,nisvastatin),a novel member of the medication class of statins,is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor.Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation.	price>
R-C-2767	YM 511 CAS:148869-05-0	Orally active,potent aromatase(CYP19)inhibitor(IC50 values are 0.4 and 0.12nM at rat ovary and human placenta cells respectively)that only weakly inhibits the synthesis of other steroid hormones.Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro(IC50=0.13nM).	price>
R-C-2768	PDN01791 CAS:149301-79-1	PDN01791（Arachidonyl Trifluoromethyl Ketone）is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group.It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s.	price>
R-C-2769	MOG (35-55) CAS:149635-73-4	Myelin oligodendrocyte glycoprotein(MOG)35-55 is a minor component of CNS myelin.Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination,common to the manifestations of multiple sclerosis.Induces strong T and B cell responses and is highly encephalitogenic.	price>
R-C-2770	JJKK 048 CAS:1515855-97-6	JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase(MAGL).	price>
R-C-2771	Cilomilast CAS:153259-65-5	Cilomilast(SB-207499)is a potent,selective and orally active inhibitor of Phosphodiesterase 4(PDE4),with IC50s of ~100 and 120nM for LPDE4 and HPDE4,respectively.Cilomilast shows selectivity for PDE4 over PDE1,PDE2,PDE3 and PDE5(IC50=74,65,>100,and 83µM,respectively).	price>

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