Catalog name Description price
R-R-3117 8-OH-DPAT hydrobromide CAS No.76135-31-4 8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide/CAS No.76135-31-4 is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site. price>
R-C-1418 Siponimod (BAF312) CAS:1230487-00-9 BAF312(Siponimod)is a next-generation S1P receptor agonist,selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM,exhibits >1000-fold selectivity over S1P2,S1P3 and S1P4 receptors.  price>
R-R-3118 S1RA hydrochloride CAS No.1265917-14-3 S1RA (E-52862) hydrochloride/CAS No.1265917-14-3 is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization. price>
R-R-3119 Loxapine CAS No.1977-10-2 Loxapine/CAS No.1977-10-2 is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. price>
R-R-3120 Tandospirone CAS No.87760-53-0 Tandospirone (SM-3997)/CAS No.87760-53-0 is a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms. price>
R-R-3121 Cariprazine CAS No.839712-12-8 Cariprazine/RGH-188/CAS No.839712-12-8 is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). price>
R-R-3122 Asenapine maleate CAS No.85650-56-2 Asenapine maleate/CAS No.85650-56-2 is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with Ki values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic. price>
R-C-1423 Sertindole CAS:106516-24-9 Sertindole is one of the newer antipsychotic medications and a neuroleptic.Like the other atypical antipsychotics,it has activity at dopamine and serotonin receptors in the brain.It is used in the treatment of schizophrenia. price>
R-R-3123 Cariprazine hydrochloride CAS No.1083076-69-0 Cariprazine hydrochloride/CAS No.1083076-69-0 is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). price>
R-R-3124 Mosapride citrate CAS No.112885-42-4 Mosapride citrate/CAS No.112885-42-4 is an orally active gastroenterokinetic compound. Mosapride citrate is a 5HT4 agonist. Mosapride citrate is a CYP inducer. Mosapride citrate has a concentration-dependent inhibitory effect on Kv4.3, and its IC50 value is 15.2 μM. Mosapride citrate can be used in the study of gastrointestinal diseases. price>