Catalog |
name |
Description |
price |
R-R-3117 |
8-OH-DPAT hydrobromide CAS No.76135-31-4 |
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide/CAS No.76135-31-4 is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site. |
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R-C-1418 |
Siponimod (BAF312) CAS:1230487-00-9 |
BAF312(Siponimod)is a next-generation S1P receptor agonist,selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM,exhibits >1000-fold selectivity over S1P2,S1P3 and S1P4 receptors. |
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R-R-3118 |
S1RA hydrochloride CAS No.1265917-14-3 |
S1RA (E-52862) hydrochloride/CAS No.1265917-14-3 is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization. |
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R-R-3119 |
Loxapine CAS No.1977-10-2 |
Loxapine/CAS No.1977-10-2 is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. |
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R-R-3120 |
Tandospirone CAS No.87760-53-0 |
Tandospirone (SM-3997)/CAS No.87760-53-0 is a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms. |
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R-R-3121 |
Cariprazine CAS No.839712-12-8 |
Cariprazine/RGH-188/CAS No.839712-12-8 is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
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R-R-3122 |
Asenapine maleate CAS No.85650-56-2 |
Asenapine maleate/CAS No.85650-56-2 is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with Ki values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic. |
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R-C-1423 |
Sertindole CAS:106516-24-9 |
Sertindole is one of the newer antipsychotic medications and a neuroleptic.Like the other atypical antipsychotics,it has activity at dopamine and serotonin receptors in the brain.It is used in the treatment of schizophrenia. |
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R-R-3123 |
Cariprazine hydrochloride CAS No.1083076-69-0 |
Cariprazine hydrochloride/CAS No.1083076-69-0 is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
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R-R-3124 |
Mosapride citrate CAS No.112885-42-4 |
Mosapride citrate/CAS No.112885-42-4 is an orally active gastroenterokinetic compound. Mosapride citrate is a 5HT4 agonist. Mosapride citrate is a CYP inducer. Mosapride citrate has a concentration-dependent inhibitory effect on Kv4.3, and its IC50 value is 15.2 μM. Mosapride citrate can be used in the study of gastrointestinal diseases. |
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