Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-C-1399	ONO-7643 CAS:249921-19-5	Anamorelin(ONO-7643,RC-1291,ST-1291)is an orally active,high-affinity,selective agonist of the ghrelin receptor with an EC50 value of 0.74 nM in the HEK293/GRLN FLIPR assay.	price>
R-R-3099	Pindolol CAS No.13523-86-9	Pindolol (LB-46)/CAS No.13523-86-9 is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM).	price>
R-R-3100	Buspirone hydrochloride CAS No.33386-08-2	Buspirone hydrochloride/CAS No.33386-08-2 is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research.	price>
R-R-3101	GR 113808 CAS No.144625-51-4	GR 113808/CAS No.144625-51-4 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors.	price>
R-C-1403	BMS-986020 CAS:1257213-50-5	BMS-986020(AM152,AP-3152 free acid)is a potent and selective antagonist of lysophosphatidic acid receptor 1(LPA1).BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8μM,6.2 μM,and 7.5μM for BSEP,MRP4,and MDR3,respectively.BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis(IPF).	price>
R-R-3109	Sumatriptan succinate CAS No.103628-48-4	Sumatriptan succinate (GR 43175)/CAS No.103628-48-4 is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan succinate can be used for migraine headache research.	price>
R-R-3110	Ziprasidone CAS No.146939-27-7	Ziprasidone (CP-88059)/CAS No.146939-27-7, an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist. Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM).	price>
R-R-3111	Metergoline CAS No.17692-51-2	Metergoline/CAS No.17692-51-2 is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation.	price>
R-R-3112	Spiperone CAS No.749-02-0	Spiperone/CAS No.749-02-0 is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases.	price>
R-R-3113	Mirtazapine CAS No.85650-52-8	Mirtazapine (Org3770)/CAS No.85650-52-8 is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively.	price>

...

163