Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-C-1423	Sertindole CAS:106516-24-9	Sertindole is one of the newer antipsychotic medications and a neuroleptic.Like the other atypical antipsychotics,it has activity at dopamine and serotonin receptors in the brain.It is used in the treatment of schizophrenia.	price>
R-R-3123	Cariprazine hydrochloride CAS No.1083076-69-0	Cariprazine hydrochloride/CAS No.1083076-69-0 is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).	price>
R-R-3124	Mosapride citrate CAS No.112885-42-4	Mosapride citrate/CAS No.112885-42-4 is an orally active gastroenterokinetic compound. Mosapride citrate is a 5HT4 agonist. Mosapride citrate is a CYP inducer. Mosapride citrate has a concentration-dependent inhibitory effect on Kv4.3, and its IC50 value is 15.2 μM. Mosapride citrate can be used in the study of gastrointestinal diseases.	price>
R-R-3125	Methiothepin mesylate CAS No.74611-28-2	Methiothepin (Metitepine) mesylate/CAS No.74611-28-2 is a potent and non-selective 5-HT2 receptor antagonist, with pKds of 7.10 (5-HT1A), 7.28 (5HT1B), 7.56 (5HT1C), 6.99 (5HT1D), 7.0 (5-HT5A), 7.8 (5-HT5B), 8.74 (5-HT6), and 8.99 (5-HT7), and pKis of 8.50 (5HT2A), 8.68 (5HT2B), and 8.35 (5HT2C).	price>
R-R-3126	SB-224289 hydrochloride CAS No.180084-26-8	SB-224289 hydrochloride/CAS No.180084-26-8 is a selective 5-HT1B receptor antagonist, with anxiolytic effect.	price>
R-R-3127	SB 204741 CAS No.152239-46-8	SB 204741/CAS No.152239-46-8 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1.	price>
R-R-3128	RS-127445 hydrochloride CAS No.199864-86-3	RS-127445 hydrochloride/CAS No.199864-86-3 is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.	price>
R-C-1429	Talnetant CAS：174636-32-9	Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4nM,hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor,with no affinity for the hNK-1 at concentrations up to 100 uM.	price>
R-R-3129	Nefazodone hydrochloride CAS No.82752-99-6	Nefazodone hydrochloride (BMY-13754)/CAS No.82752-99-6 is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity.	price>
R-C-1430	Tepoxalin CAS：174636-32-9	Talnetant(SB 223412)is a potent and selective NK3 receptor antagonist(ki=1.4nM, hNK-3-CHO);100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.	price>

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