Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3084	Brexpiprazole CAS No.913611-97-9	Brexpiprazole (OPC-34712)/CAS No.913611-97-9, an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM).	price>
R-C-1385	Capadenoson,BAY 68-4986 CAS:544417-40-5	Capadenoson is a selective agonist of adenosine-A1 receptor.	price>
R-R-3085	SEP-363856 hydrochloride CAS No.1310422-41-3	SEP-363856 hydrochloride (SEP-856 hydrochloride)/CAS No.1310422-41-3, an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 hydrochloride (SEP-856 hydrochloride) has the potential for the study of schizophrenia.	price>
R-R-3086	Volinanserin CAS No.139290-65-6	Volinanserin/CAS No.139290-65-6 is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity.	price>
R-C-1387	Preladenant CAS:377727-87-2	Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a Ki of 1.1 nM and has over 1000-fold selectivity over other adenosine receptors.	price>
R-R-3087	Ritanserin CAS No.87051-43-2	Ritanserin (R 55667)/CAS No.87051-43-2 is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.	price>
R-R-3088	Paliperidone CAS No.144598-75-4	Paliperidone (9-Hydroxyrisperidone)/CAS No.144598-75-4, the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia.	price>
R-R-3089	Vortioxetine hydrobromide CAS No.960203-27-4	Vortioxetine hydrobromide/CAS No.960203-27-4 is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.	price>
R-R-3090	WAY-100635 maleate CAS No.1092679-51-0	WAY-100635 maleate/CAS No.1092679-51-0 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D4 receptor agonist.	price>
R-R-3091	8-OH-DPAT CAS No.78950-78-4	8-OH-DPAT /CAS No.78950-78-4 is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).	price>

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