Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-2782	MK-3207 Hydrochloride CAS No.957116-20-0	MK-3207 (Hydrochloride)/CAS No.957116-20-0 is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.	price>
R-R-2783	Atogepant CAS No.1374248-81-3	Atogepant (MK-8031)/CAS No.1374248-81-3 is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.	price>
R-R-2784	Adrenomedullin (1-50), rat	Adrenomedullin (1-50), rat is a 50 amino acid peptide, which induces a selective arterial vasodilation via activation of CGRP1 receptor.	price>
R-R-2785	Calcitonin Gene Related Peptide (CGRP) II, rat TFA	Calcitonin Gene Related Peptide (CGRP) II, rat TFA, a CGRP receptor activator, is a potent and long-lasting vasodilator. Calcitonin Gene Related Peptide (CGRP) II TFA can be used in the research of cardiovascular diseases.	price>
R-R-2786	SUN B8155 CAS No.345893-91-6	SUN B8155/CAS No.345893-91-6, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis.	price>
R-R-2787	Adrenomedullin (16-31), human CAS No.318480-38-5	Adrenomedullin (16-31), human/CAS No.318480-38-5 is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor activity in the systemic vascular bed of the rat, but not the cat.	price>
R-R-2788	Chrysin 6-C-glucoside 8-C-arabinoside CAS No.185145-34-0	Chrysin 6-C-glucoside 8-C-arabinoside/CAS No.185145-34-0 can inhibit the CGRP releasing and the activation of TRPV1 channel. Chrysin 6-C-glucoside 8-C-arabinoside can be used for anti-migraine research.	price>
R-R-2789	(3R,5R,6S)-Atogepant	(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant (HY-109022). Atogepant is a calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.	price>
R-R-2790	R121919 CAS No.195055-03-9	R121919 (NBI30775)/CAS No.195055-03-9 is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats.	price>
R-C-1091	CP945598.HCl CAS：686347-12-6	CP 945598 hydrochloride(Otenabant HCl)is a potent and selective cannabinoid type 1 receptor antagonist that inhibits both basal and cannabinoid agonist-mediated CB(1)receptor signaling in vitro and in vivo.It displays low affinity for human CB2 receptors with Ki of 7600 nM. In vivo,CP-945598 reversed cannabinoid agonist-mediated responses,reduced food intake,and increased energy expenditure and fat oxidation in rodents.CP 945598 exhibits dose and concentration-dependent anorectic activity in two models of acute food intake in rodents,fast-induced re-feeding and spontaneous,nocturnal feeding.CP-945598 also acutely stimulates energy expenditure in rats and decreases the respiratory quotient indicating a metabolic switch to increased fat oxidation.	price>

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