Catalog name Description price
R-R-2774 Pramlintide acetate CAS No.187887-46-3 Pramlintide acetate/CAS No.187887-46-3 is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer. price>
R-R-2775 a-CGRP (mouse, rat) (TFA) α-CGRP (mouse, rat) TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) TFA can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) TFA has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies. price>
R-R-2776 Cagrilintide acetate Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies. price>
R-R-2777 b-CGRP, human TFA β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells. price>
R-R-2778 Olcegepant hydrochloride CAS No.586368-06-1 Olcegepant hydrochloride (BIBN-4096 hydrochloride)/CAS No.586368-06-1 is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide receptor 1 (CGRP1) with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. price>
R-R-2779 Telcagepant CAS No.781649-09-0 Telcagepant (MK-0974)/CAS No.781649-09-0 is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with Kis of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively. price>
R-R-2780 BCTC CAS No.393514-24-4 BCTC/CAS No.393514-24-4 is an orally active current inhibitor of vanilloid receptor type 1 (VR1). BCTC is a transient receptor potential cation channel subfamily M member 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) antagonist. BCTC is an insulin sensitizer and secretor. BCTC has anticancer and analgesic effects. price>
R-R-2781 MK-3207 CAS No.957118-49-9 MK-3207/CAS No.957118-49-9 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC50=0.12 nM; Ki=0.024 nM). MK-3207 can be used for migraine studies. price>
R-R-2782 MK-3207 Hydrochloride CAS No.957116-20-0 MK-3207 (Hydrochloride)/CAS No.957116-20-0 is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3. price>
R-R-2783 Atogepant CAS No.1374248-81-3 Atogepant (MK-8031)/CAS No.1374248-81-3 is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine. price>