Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-2764	(S)-4CPG CAS No.134052-73-6	(S)-4CPG ((S)-4-Carboxyphenylglycine)/CAS No.134052-73-6 is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases.	price>
R-R-2765	CBiPES CAS No.353235-01-5	CBiPES/CAS No.353235-01-5 is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases.	price>
R-R-2766	SIB-1757 CAS No.31993-01-8	SIB-1757/CAS No.31993-01-8 is a highly selective and noncompetitive antagonist of mGlu5 receptor with an IC50 of 0.4 μM.	price>
R-R-2768	CBiPES hydrochloride CAS No.856702-40-4	CBiPES hydrochloride/CAS No.856702-40-4 is a mGlu2 receptor positive allosteric modulator (EC50: 92.8 nM). CBiPES hydrochloride attenuates stress-induced hyperthermia and PCP-induced hyperlocomotor activity. CBiPES hydrochloride can be used for research of neurological disease.	price>
R-C-1069	REVERSINE CAS：656820-32-5	Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM,respectively.Also used for stem cell dedifferentiation.	price>
R-R-2769	(S,S)-BMS-984923 CAS No.1375752-77-4	(S,S)-BMS-984923/CAS No.1375752-77-4 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor. BMS-984923 is a potent mGluR5 silent allosteric modulator. (S,S)-BMS-984923 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-2770	ML289 CAS No.1382481-79-9	ML289 (VU0463597)/CAS No.1382481-79-9 is a potent, selective, and CNS-penetrant mGlu3 (IC50=0.66 μM) negative allosteric modulator. ML289 displays >15-fold selectivity over mGlu2 and is inactive against mGlu5. ML289 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-2771	VU0469650 CAS No.1443748-47-7	VU0469650/CAS No.1443748-47-7 is a potent, selective and CNS-penetrated negative allosteric modulator of mGlu1 receptor, with an IC50 of 99 nM.	price>
R-R-2772	ZJ43 CAS No.723331-20-2	ZJ43/CAS No.723331-20-2 is a potent NAAG peptidase inhibitor, with an IC50 of 2.4 nM and a Ki of 0.8 nM. ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models.	price>
R-R-2773	FEMA 4774 CAS No.1359963-68-0	FEMA 4774/CAS No.1359963-68-0 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer.	price>

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