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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4255 Kynurenic acid sodium CAS No.2439-02-3 Kynurenic acid sodium/CAS No.2439-02-3, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. price>
R-R-4256 Nicotinamide N-oxide CAS No.1986-81-8 Nicotinamide N-oxide/CAS No.1986-81-8, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. price>
R-R-4257 Burixafor hydrobromide CAS No.1191450-19-7 Burixafor hydrobromide (TG-0054 hydrobromide)/CAS No.1191450-19-7 is an orally bioavailable and potent antagonist of CXCR4 and a well anti-angiogenic drug that is of potential value in treating choroid neovascularization. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction. price>
R-R-4258 FC131 TFA CAS No.842166-42-1 FC131 TFA/CAS No.842166-42-1 is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity. price>
R-R-4259 Elubrixin tosylate CAS No.960495-43-6 Elubrixin tosylate (SB-656933 tosylate)/CAS No.960495-43-6 is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation. price>
R-R-4260 CXCR2-IN-1 CAS No.1873376-49-8 CXCR2-IN-1/CAS No.1873376-49-8 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3. price>
R-R-4261 AMD 3465 hexahydrobromide CAS No.185991-07-5 AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide)/CAS No.185991-07-5 is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses. price>
R-R-4262 CXCR7 modulator 2 CAS No.2227426-37-9 CXCR7 modulator 2/CAS No.2227426-37-9 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. price>
R-R-4263 CXCR2 antagonist 8 CAS No.182498-30-2 CXCR2 antagonist 8/CAS No.182498-30-2 is a potent and selective CXCR2 antagonist. CXCR2 antagonist 8 can be used for insulin resistance research. price>
R-R-4264 CXCR7 antagonist-1 hydrochloride CAS No.2990472-61-0 CXCR7 antagonist-1 hydrochloride/CAS No.2990472-61-0 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases (extracted from patent WO2014085490A1, compound 1.128). price>