Products classification
ABOUT US
Email:
sales@ruixibiotech.com
Tel.:
02988811435
Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4258 FC131 TFA CAS No.842166-42-1 FC131 TFA/CAS No.842166-42-1 is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity. price>
R-R-4259 Elubrixin tosylate CAS No.960495-43-6 Elubrixin tosylate (SB-656933 tosylate)/CAS No.960495-43-6 is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation. price>
R-R-4260 CXCR2-IN-1 CAS No.1873376-49-8 CXCR2-IN-1/CAS No.1873376-49-8 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3. price>
R-R-4261 AMD 3465 hexahydrobromide CAS No.185991-07-5 AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide)/CAS No.185991-07-5 is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses. price>
R-R-4262 CXCR7 modulator 2 CAS No.2227426-37-9 CXCR7 modulator 2/CAS No.2227426-37-9 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. price>
R-R-4263 CXCR2 antagonist 8 CAS No.182498-30-2 CXCR2 antagonist 8/CAS No.182498-30-2 is a potent and selective CXCR2 antagonist. CXCR2 antagonist 8 can be used for insulin resistance research. price>
R-R-4264 CXCR7 antagonist-1 hydrochloride CAS No.2990472-61-0 CXCR7 antagonist-1 hydrochloride/CAS No.2990472-61-0 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases (extracted from patent WO2014085490A1, compound 1.128). price>
R-R-4265 Ladarixin sodium CAS No.865625-56-5 Ladarixin sodium (DF 2156A)/CAS No.865625-56-5 is an orally active, allosteric non-competitive and dual CXCR1 and CXCR2 antagonist. Ladarixin sodium can be used for the research of COPD and asthma. price>
R-R-4266 ATI-2341 TFA ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4), which functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs). price>
R-R-4267 USL311 CAS No.1373268-67-7 USL311/CAS No.1373268-67-7 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. price>