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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4279 AZD8309 CAS No.333742-48-6 AZD8309 is an orally active antagonist of CXCR2. AZD8309 has the ability to regulate the transmigration of neutrophils. AZD8309 can be used in the study of inflammatory diseases. price>
R-R-4280 ACT-660602 CAS No.1646267-59-5 ACT-660602/CAS No.1646267-59-5 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. ACT-660602 inhibits T-cell migration and shows efficacy in acute lung ingury model. ACT-660602 can be used for autoimmune diseases research. price>
R-R-4281 SCH 563705 CAS No.473728-58-4 SCH 563705/CAS No.473728-58-4 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively. price>
R-R-4282 CTCE-0214 CAS No.577782-52-6 CTCE-0214/CAS No.577782-52-6 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research. price>
R-R-4283 SRT3109 CAS No.1204707-71-0 SRT3109/CAS No.1204707-71-0 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases. price>
R-R-4284 Plerixafor-d4 CAS No.1246819-87-3 Plerixafor-d4/CAS No.1246819-87-3 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM. price>
R-R-4285 SB-332235 CAS No.276702-15-9 SB-332235/CAS No.276702-15-9 is a potent, orally active nonpeptide CXCR2 antagonist, with an IC50 of 7.7 nM. SB-332235 displays 285-fold selectivity for CXCR2 over CXCR1. SB-332235 inhibits acute and chronic models of arthritis in the rabbit. SB-332235 inhibits viability of AML cells. price>
R-R-4286 CXCR2 antagonist 2 CAS No.2647464-91-1 CXCR2 antagonist 2/CAS No.2647464-91-1 is a potent CXCR2 antagonist for cancer immunoresearch with an IC50 value of 95 nM. price>
R-R-4287 MPTP hydrochloride CAS No.23007-85-4 MPTP hydrochloride/CAS No.23007-85-4 is a brain-penetrating dopamine neurotoxin, inducing Parkinson disease. MPTP hydrochloride, precursor of MPP+, induces apoptosis. price>
R-R-4288 Oxidopamine hydrochloride CAS No.28094-15-7 Oxidopamine (6-OHDA) hydrochloride/CAS No.28094-15-7 is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. price>