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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4285 SB-332235 CAS No.276702-15-9 SB-332235/CAS No.276702-15-9 is a potent, orally active nonpeptide CXCR2 antagonist, with an IC50 of 7.7 nM. SB-332235 displays 285-fold selectivity for CXCR2 over CXCR1. SB-332235 inhibits acute and chronic models of arthritis in the rabbit. SB-332235 inhibits viability of AML cells. price>
R-R-4286 CXCR2 antagonist 2 CAS No.2647464-91-1 CXCR2 antagonist 2/CAS No.2647464-91-1 is a potent CXCR2 antagonist for cancer immunoresearch with an IC50 value of 95 nM. price>
R-R-4287 MPTP hydrochloride CAS No.23007-85-4 MPTP hydrochloride/CAS No.23007-85-4 is a brain-penetrating dopamine neurotoxin, inducing Parkinson disease. MPTP hydrochloride, precursor of MPP+, induces apoptosis. price>
R-R-4288 Oxidopamine hydrochloride CAS No.28094-15-7 Oxidopamine (6-OHDA) hydrochloride/CAS No.28094-15-7 is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. price>
R-R-4289 SKF 81297 CAS No.71636-61-8 SKF 81297/CAS No.71636-61-8 is a potent and selective dopamine D1 receptor agonist. price>
R-R-4290 Fallypride CAS No.166173-78-0 Fallypride/CAS No.166173-78-0 is a potent antagonist of dopamine D2/D3 receptor. Fallypride, in the form of fallypride (18F), can be used as a positron emission tomography (PET) radiotracer. price>
R-C-2591 GRI 977143 CAS:325850-81-5 GRI977143 is a selective lysophosphatidic acid 2(LPA2)receptor non-lipid agonist (EC50=3.3μM).GRI977143 does not activate other LPA GPCRs at concentrations up to 10μM. price>
R-R-4291 Octoclothepin maleate salt CAS No.4789-68-8 Octoclothepin maleate salt/CAS No.4789-68-8, an orally active neuroleptic agent, is a dual SR-2A and D2DR inhibitor. Octoclothepin maleate salt reveals an intensive central depressant action in a series of observational and instrumental procedures in rodents. price>
R-R-4292 Clozapine N-oxide dihydrochloride CAS No.2250025-93-3 Clozapine N-oxide dihydrochloride/CAS No.2250025-93-3 is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist. price>
R-R-4293 SKF 38393 hydrochloride CAS No.62717-42-4 SKF 38393 hydrochloride/CAS No.62717-42-4 is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM. price>