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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4250 IT1t dihydrochloride CAS No.1092776-63-0 IT1t dihydrochloride/CAS No.1092776-63-0 is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. price>
R-R-4251 PS372424 hydrochloride CAS No.1596362-29-6 PS372424 hydrochloride/CAS No.1596362-29-6, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 hydrochloride prevents human T-cell migration in a humanized model of arthritic inflammation. price>
R-R-4252 Reparixin L-lysine salt CAS No.266359-93-7 Reparixin L-lysine salt/CAS No.266359-93-7 is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation. price>
R-R-4253 TC14012 CAS No.368874-34-4 TC14012/CAS No.368874-34-4, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-HIV activity and anti-cancer activity. price>
R-R-4254 Kynurenic acid-d5 CAS No.350820-13-2 Kynurenic acid-d5/CAS No.350820-13-2 is the deuterium labeled Kynurenic acid. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. price>
R-R-4255 Kynurenic acid sodium CAS No.2439-02-3 Kynurenic acid sodium/CAS No.2439-02-3, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. price>
R-R-4256 Nicotinamide N-oxide CAS No.1986-81-8 Nicotinamide N-oxide/CAS No.1986-81-8, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. price>
R-R-4257 Burixafor hydrobromide CAS No.1191450-19-7 Burixafor hydrobromide (TG-0054 hydrobromide)/CAS No.1191450-19-7 is an orally bioavailable and potent antagonist of CXCR4 and a well anti-angiogenic drug that is of potential value in treating choroid neovascularization. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction. price>
R-R-4258 FC131 TFA CAS No.842166-42-1 FC131 TFA/CAS No.842166-42-1 is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity. price>
R-R-4259 Elubrixin tosylate CAS No.960495-43-6 Elubrixin tosylate (SB-656933 tosylate)/CAS No.960495-43-6 is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation. price>