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Catalog	name	Description	price
R-C-2446	Vorinostat (SAHA) CAS:149647-78-9	Vorinostat(suberanilohydroxamic acid)MK-0683 and SAHA,is a potent and selective inhibitor of histone deace tylases (HDACs).Vorinostat has been shown to bind to the active site of histone deacetylases and act as a chelator for Zinc ions also found in the active site of histone deacetylases.	price>
R-C-2449	AR-42 CAS：935881-37-1	AR-42((S)-HDAC-42):AR-42;NSC-736012;OSU-42;OSU-HDAC-42;OSUHDAC-42.AR-42 may possess additional histone-independent mechanisms,which may contribute to its superior profile in vitro and in vivo.	price>
R-C-2486	EX-527 CAS:49843-98-3	Selisistat(EX-527)is a SirT1 inhibitor for treatment of Huntington is disease. EX-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism.Ex-527 is widely used as a major inhibitor of Sirtuin enzymes,which are a family of highly conserved protein deacetylases and have been linked with caloric restriction and aging by modulating energy metabolism,genomic stability, and stress resistance.	price>
R-C-2497	UNC-0638 CAS：1255580-76-7	UNC0638 selectively inhibits G9a and GLP histone methyltransferase activity with IC50s of less than 15nM and 19nM,respectively.UNC0638 has anti-FMDV(foot-and-mouth disease virus)and anti-VSV(vesicular stomatitis virus)activities.	price>
R-C-2502	BMS 986158 CAS：1800340-40-2	BMS-986158 is a potent BET inhibitor with IC50s of 6.6 and 5nM in NCI-H211 small cell lung cancer(SCLC)cells and MDA-MB231 triple negative breast cancer(TNBC)cells,respectively.	price>
R-C-2678	Trichostatin A (TSA) CAS：58880-19-6	Trichostatin A(TSA)is a potent and specific inhibitor of HDAC class I/II,with an IC50 value of 1.8nM for HDAC.	price>
R-C-2690	SGI-1027 CAS：1020149-73-8	SGI-1027 is a DNA methyltransferase(DNMT)inhibitor,with IC50s of 7.5μM,8μM, and 12.5 μM for DNMT3B,DNMT3A,and DNMT1 with poly(dI-dC)as substrate.	price>
R-C-2695	Lestaurtinib CAS：111358-88-4	Lestaurtinib(CEP-701;KT-5555)is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases.Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9,3 and less than 25nM,respectively.	price>
R-C-2697	UNC 0224 CAS：1197196-48-7	UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6nM,an IC50 of 15nM and a Kd of 23nM.UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58nM.	price>
R-C-2700	UNC0321 CAS：1238673-32-9	UNC0321 is the first G9a inhibitor with picomolar potency and the most potent G9a inhibitor to date.Protein lysine methyltransferase G9a,which catalyzes methylation of lysine 9 of histone H3(H3K9)and lysine 373(K373)of p53,is overexpressed in human cancers.	price>

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