Product apis-epigentics

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Catalog	name	Description	price
R-R-2603	iBRD4-BD1 diTFA CAS No.2839318-20-4	iBRD4-BD1 diTFA/CAS No.2839318-20-4 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology.	price>
R-R-2604	ZEN-3219 CAS No.1952264-34-4	ZEN-3219/CAS No.1952264-34-4 is a BET inhibitor with IC50s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4.	price>
R-R-2605	(+)-JQ-1-aldehyde CAS No.2634778-37-1	(+)-JQ-1-aldehyde/CAS No.2634778-37-1 is the aldehyde form of (+)-JQ1. (+)-JQ-1-aldehyde can be uesd as a precursor to synthesize PROTACs, which targets BET bromodomains.	price>
R-R-2606	OXFBD04 CAS No.2231747-03-6	OXFBD04/CAS No.2231747-03-6 is a potent and selective BRD4 inhibitor with an IC50 of 166 nM. OXFBD04 is a potent BET bromodomain ligand with additional modest affinity for the CREBBP bromodomain. OXFBD04 has anti-cancer activity.	price>
R-R-2607	Menin-MLL inhibitor-22 CAS No.2851841-61-5	Menin-MLL inhibitor-22 (compound C20)/CAS No.2851841-61-5 is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome).	price>
R-R-2608	PROTAC BRD4 Degrader-10 CAS No.2417370-49-9	PROTAC BRD4 Degrader-10 (compound 8b)/CAS No.2417370-49-9 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.	price>
R-R-2609	Bromodomain inhibitor-8 CAS No.1300031-70-2	Bromodomain inhibitor-8 (Intermediate 21)/CAS No.1300031-70-2 is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases.	price>
R-R-2610	UNC1021 CAS No.1322591-19-4	UNC1021/CAS No.1322591-19-4 is a selective L3MBTL3 inhibitor with an IC50 of 0.048 μM.	price>
R-R-2611	PROTAC BRD9 Degrader-6 CAS No.2676211-62-2	PROTAC BRD9 Degrader-6/CAS No.2676211-62-2 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders.	price>
R-C-1008	PFI-1 (PF-6405761) cas:1403764-72-6	PFI-1(PF-6405761)is a highly selective BET(bromodomain-containing protein)inhibitor for BRD4 with IC50 of 0.22 μM and for BRD2 with IC50 of 98 nM in a cell-free assay.	price>

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