Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-C-1955	Fludarabine phosphate CAS:75607-67-9	Fludarabine Phosphate(F-ara-A,NSC 312887)is an analogue of adenosine and deoxyadenosine,which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.	price>
R-C-1969	AZ31 CAS：2088113-98-6	AZ31 is a potent and highly selective ATM inhibitor.	price>
R-C-1996	PF-06687859（RG3039) CAS:1005504-62-0	RG3039(PF-06687859)is a potent DcpS inhibitor.DcpS is a therapeutic target for spinal muscular atrophy.Spinal muscular atrophy(SMA)is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN.RG3039 improves motor function in SMA mice.	price>
R-C-2031	Mirin CAS：1198097-97-0	Mirin prevents ATM activation in response to double strand breaks(IC50=12uM)and induces G2 cell cycle arrest.	price>
R-C-2043	TH5487 CAS：2304947-71-3	TH5487 is a potent 8-oxoguanine DNA glycosylase 1(OGG1)inhibitor with an IC50 of 342 nM.TH5487 stops OGG1 from recognizing its DNA substrate,inhibits DNA repair and modifies OGG1 chromatin dynamics,which results in the inhibition of proinflammatory pathway genes.	price>
R-C-2065	AZ6102 CAS：1645286-75-4	AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor,with IC50s of 3 nM and 1 nM,respectively,and alao has 100-fold selectivity against other PARP family enzymes,with IC50s of 2.0μM,0.5μM,and>3μM,for PARP1,PARP2,and PARP6, respectively.	price>
R-C-2073	Oxaliplatin CAS：61825-94-3	Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane(DACH)and with an oxalate ligand as a leaving group.A leaving group is an atom or a group of atoms that is displaced as a stable species taking with it the bonding electrons.The DACH side chain appears to inhibit alkylating-agent resistance.	price>
R-C-2106	GSK3117391 CAS：1018673-42-1	GSK3117391(GSK3117391A)and HDAC-IN-3,is a potent HDAC inhibitor for treating chronic inflammatory disorders.	price>
R-C-2120	CL2A-SN-38 CAS：1279680-68-0	CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate(ADC).CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types.	price>
R-C-2132	Favipiravir (T-705)	Favipiravir(T-705)is a potent viral RNA polymerase inhibitor,it is phosphoribosylated by cellular enzymes to its active form,Favipiravir-ribofuranosyl-5-triphosphate(RTP).Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase(RdRP)activity with an IC50 of 341nM.	price>

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