Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-C-1454	NCH 51 CAS:848354-66-5	PTACH(NCH-51)is a potent HDAC inhibitor with IC50s of 48 nM,32 nM,and 41 nM for HDAC1,HDAC4,and HDAC6,respectively.PTACH exerts potent growth inhibition against various cancer cells(EC50s of 1.1-9.1 µM) .	price>
R-C-1485	Bleomycin Sulfate(NSC125066) CAS：9041-93-4	Bleomycin Sulfate(NSC125066)is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas(SCC)with IC50 of 4 nM in UT-SCC-19A cells.	price>
R-C-1486	Carboplatin (NSC 241240) CAS：41575-94-4	Carboplatin is a chemotherapy drug used against some forms of cancer(mainly ovarian carcinoma,lung,head and neck cancers).Cisplatin and carboplatin,as well as oxaliplatin,interact with DNA,akin to the mechanism of alkylating agents.	price>
R-C-1495	Daptomycin CAS:103060-53-3	Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.	price>
R-C-1514	T0070907 CAS：313516-66-4	T0070907 is a potent and selective PPARγinhibitor with IC50 of 1 nM in a cell-free assay,with a>800-fold selectivity over PPARα and PPARδ.T0070907 significantly decreases the levels of DNA-PKcs and RAD51 proteins in ME-180 and SiHa cells.	price>
R-C-1521	Compound 401 CAS：168425-64-7	Compound 401 is a synthetic inhibitor of DNA-PK(IC50=0.28 μM) and mTOR(IC50=5.3μM).It has no inhibition on p110α/p85α PI3K(>100 μM) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.	price>
R-C-1542	Etoposide CAS:33419-42-0	Etoposide(VP-16,VP-16213)is a semisynthetic derivative of podophyllotoxin,which inhibits DNA synthesis via topoisomerase II inhibition activity.Etoposide induces autophagy,mitophagy and apoptosis.	price>
R-C-1551	Tubercidin CAS:69-33-0	Tubercidin(7-deaza-adenosine),an adenosine analogue,is a nucleoside antibiotic.It is incorporated into DNA and inhibits polymerases,thereby inhibiting DNA replication and RNA and protein synthesis.This agent also exhibits antifungal and antiviral activities.	price>
R-C-1588	Scriptaid CAS:287383-59-9	Scriptaid is a potent histone deacetylase(HDAC)inhibitor,used in cancer research.Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus(EBV)-associated lymphomas treatment.	price>
R-C-1593	LMK-235 CAS:1418033-25-6	LMK-235 is a potent and selective HDAC4/5 inhibitor,inhibits HDAC5,HDAC4, HDAC6,HDAC1,HDAC2,HDAC11 and HDAC8,with IC50s of 4.22 nM,11.9nM,55.7nM,320 nM,881 nM,852 nM and 1278 nM,respectively,and is used in cancer research.	price>

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