Catalog |
name |
Description |
price |
R-R-4962 |
Tenofovir exalidex CAS No.911208-73-6 |
Tenofovir exalidex (CMX157)/CAS No.911208-73-6 is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV. |
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R-R-5674 |
α-2-Deoxy Zebularine CAS: 68780-64-350 |
α-2-Deoxy Zebularine/1-(2-Deoxy-α-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone/CAS: 68780-64-350 is a chemically stable cytidine analog . It has been shown to inhibit DNA methylation and tumor growth both in vitro and in vivo . It is also known to act as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates . |
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R-C-5381 |
Rifalogue cas:845625-44-7 |
The CAS number 845625-44-7 refers to a chemical compound with the systematic name (3S,4R)-3-(1S)-4-amino-2-methylbutan-2-yl-1-(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl-4-methylpyrrolidin-2-one. This is a cholinesterase inhibitor and has potential therapeutic applications for the treatment of Alzheimers disease and other cognitive disorders. However, further research and development are necessary to determine its safety and effectiveness. |
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R-C-5903 |
N-Stearoyl-D-sphingosine CAS:2304-81-6 |
Cer(d18:1/18:0),(2S,3R,4E)-2-(Stearoylamino)-4-octadecene-1,3-diol,N-Octadecanoyl-D-sphingosine,N-Stearoyl-D-erythro-sphingosine,N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide,C18 Ceramide (d18:1/18:0),C18-Ceramide,C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1(Lass1) in mice. Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells. |
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R-C-6182 |
Camptothecin CAS:7689-03-4 |
Camptothecin(CPT)is a potent DNA enzyme topoisomerase I (topo I) inhibitor.It was isolated from the bark and stem of Camptotheca acuminata(Camptotheca,Happy tree). |
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R-C-6183 |
Cisplatin CAS:15663-27-1 |
Cisplatin is a potent inducer of growth arrest and or apoptosis in most cell types.Cisplatin is an inorganic platinum agent(cis-diamminedichloroplatinum)with antineoplastic activity.Cisplatin forms highly reactive,charged,platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA,inducing intrastrand and interstrand DNA cross-links,as well as DNA-protein cross-links.These cross-links result in apoptosis and cell growth inhibition. |
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