Catalog name Description price
R-R-4962 Tenofovir exalidex CAS No.911208-73-6 Tenofovir exalidex (CMX157)/CAS No.911208-73-6 is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV. price>
R-R-5674 α-2-Deoxy Zebularine CAS: 68780-64-350 α-2-Deoxy Zebularine/1-(2-Deoxy-α-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone/CAS: 68780-64-350 is a chemically stable cytidine analog . It has been shown to inhibit DNA methylation and tumor growth both in vitro and in vivo . It is also known to act as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates . price>
R-C-5381 Rifalogue  cas:845625-44-7 The CAS number 845625-44-7 refers to a chemical compound with the systematic name (3S,4R)-3-(1S)-4-amino-2-methylbutan-2-yl-1-(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl-4-methylpyrrolidin-2-one. This is a cholinesterase inhibitor and has potential therapeutic applications for the treatment of Alzheimers disease and other cognitive disorders. However, further research and development are necessary to determine its safety and effectiveness. price>
R-C-5903 N-Stearoyl-D-sphingosine CAS:2304-81-6 Cer(d18:1/18:0),(2S,3R,4E)-2-(Stearoylamino)-4-octadecene-1,3-diol,N-Octadecanoyl-D-sphingosine,N-Stearoyl-D-erythro-sphingosine,N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide,C18 Ceramide (d18:1/18:0),C18-Ceramide,C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1(Lass1) in mice. Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells. price>
R-C-6182 Camptothecin CAS:7689-03-4 Camptothecin(CPT)is a potent DNA enzyme topoisomerase I (topo I) inhibitor.It was isolated from the bark and stem of Camptotheca acuminata(Camptotheca,Happy tree). price>
R-C-6183 Cisplatin CAS:15663-27-1 Cisplatin is a potent inducer of growth arrest and or apoptosis in most cell types.Cisplatin is an inorganic platinum agent(cis-diamminedichloroplatinum)with antineoplastic activity.Cisplatin forms highly reactive,charged,platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA,inducing intrastrand and interstrand DNA cross-links,as well as DNA-protein cross-links.These cross-links result in apoptosis and cell growth inhibition. price>