Catalog |
name |
Description |
price |
R-R-4936 |
Peldesine CAS No.133432-71-0 |
Peldesine (BCX 34)/CAS No.133432-71-0 is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research.At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Peldesine dihydrochloride) usually boasts enhanced water solubility and stability. |
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R-R-4937 |
2-Deoxy-N3-methylcytidine hydriodide CAS No.79043-77-9 |
2-Deoxy-N3-methylcytidine hydriodide/CAS No.79043-77-9 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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R-R-4938 |
Alpha-Adenosine CAS No.5682-25-7 |
Alpha-Adenosine/CAS No.5682-25-7 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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R-R-4939 |
Nucleoside-Analog-2 CAS No.876708-01-9 |
Nucleoside-Analog-2/CAS No.876708-01-9 is a 4-Azidocytidine analogue against Hepatitis C virus (HCV) replication. Nucleoside-Analog-2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. |
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R-R-4940 |
N-6-Methyl-2-deoxyadenosine-d3 CAS No.1354782-02-7 |
N-6-Methyl-2-deoxyadenosine-d3/CAS No.1354782-02-7 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. |
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R-R-4941 |
KIN59 CAS No.4152-77-6 |
KIN59 (5-O-Tritylinosine)/CAS No.4152-77-6 is a potent thymidine phosphorylase allosteric inhibitor. KIN59 inhibits FGF2-stimulated cell growth. KIN59 inhibits the expression of p-FGFR1, P-Akt in FGF2 (10 ng/mL) stimulated cells. KIN59 shows anti-tumor activity. |
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R-R-4942 |
2-Deoxy-N4-methylcytidine CAS No.22882-02-6 |
2-Deoxy-N4-methylcytidine/CAS No.22882-02-6 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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R-R-4943 |
Raluridine CAS No.119644-22-3 |
Raluridine/CAS No.119644-22-3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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R-R-4944 |
6-O-Methyldeoxyguanosine CAS No.964-21-6 |
O6-Methyldeoxy guanosine/CAS No.964-21-6; DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
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R-R-4945 |
6-Mercaptopurine-13C2,15N CAS No.1190008-04-8 |
6-Mercaptopurine-13C2,15N/CAS No.1190008-04-8 is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent. |
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