Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4604	Fidaxomicin CAS No.873857-62-6	Fidaxomicin (OPT-80)/CAS No.873857-62-6, a macrocyclic antibiotic, is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti-Clostridium difficile activity (MIC90=0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research.	price>
R-R-4605	Cytarabine hydrochloride CAS No.69-74-9	Cytarabine hydrochloride/CAS No.69-74-9, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.	price>
R-R-4606	PolQi2 CAS No.2565638-16-4	PolQi2/CAS No.2565638-16-4 inhibits the helicase activity of Polθ. PolQi2 improves the precision of gene editing at various loci and in different cell lines.	price>
R-R-4607	HRO761 CAS No.2869954-34-5	HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42)/CAS No.2869954-34-5 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research.	price>
R-R-4608	AOH1160 CAS No.2089314-57-6	AOH1160/CAS No.2089314-57-6 is a potent oral small molecule proliferating cell nuclear antigen (PCNA) inhibitor that interferes with DNA replication, blocks homologous recombination-mediated DNA repair, leads to cell cycle arrest and induces apoptosis.	price>
R-R-4609	Pseudouridine CAS No.1445-07-4	Pseudouridine/CAS No.1445-07-4 is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation.	price>
R-R-4610	ART812 CAS No.2607138-82-7	ART812/CAS No.2607138-82-7 is an orally active DNA polymerase Polθ inhibitor with an IC50 value of 7.6 nM. ART812 has an IC50 value of 240 nM for cell based microhomology-mediated end joining (MMEJ).	price>
R-R-4611	N1-Methylpseudouridine CAS No.13860-38-3	N1-methyl-pseudouridine (1-Methylpseudouridine)/CAS No.13860-38-3, a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.	price>
R-R-4612	Trimetrexate CAS No.52128-35-5	Trimetrexate (CI-898)/CAS No.52128-35-5 is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.	price>
R-R-4613	Nedaplatin CAS No.95734-82-0	Nedaplatin (NSC 375101D)/CAS No.95734-82-0 is a derivative of cisplatin and DNA damage agent.	price>

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