Product apis-cell-cycle

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Catalog	name	Description	price
R-C-1742	PD166285 CAS:185039-89-8	PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations(IC50=24nM for Wee1 and 72 nM for Myt1).PD0166285 is also a novel G2 checkpoint abrogator.PD0166285 induces apoptosis.	price>
R-C-1776	PE859 CAS:1402727-29-0	PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2μM,respectively.	price>
R-C-1777	Oxamflatin CAS:151720-43-3	Oxamflatin is a potent HDAC inhibitor,inhibiting the growth of mouse and human cancer cell lines.	price>
R-C-1789	Scriptaid (GCK 1026) CAS：287383-59-9	Scriptaid is a potent histone deacetylase(HDAC)inhibitor,used in cancer research.Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus(EBV)-associated lymphomas treatment.	price>
R-C-1793	ID-8 CAS:147591-46-6	ID-8 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase(DYRK).ID-8 sustains embryonic stem cell(ESC)self-renewal and pluripotency.ID-8 enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs.	price>
R-C-1831	Hydroxyfasudil hydrochloride(HA-1100) CAS:155558-32-0	Hydroxyfasudil hydrochloride is a ROCK inhibitor,with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2,respectively.	price>
R-C-1837	ZINC00881524 (ROCK inhibitor) CAS:557782-81-7	ZINC00881524 is a potent and selective ROCK inhibitor.Clinically,inhibition of ROCK pathway is believed to contribute to some of the cardiovascular benefits of statin therapy that are independent of lipid lowering(ie,pleiotropic effects).	price>
R-C-1844	MBX-8025 (seladelpar) CAS: 851528-79-5	Seladelpar(MBX-8025)is an orally active,potent(50% effect concentration EC50 2nM),and specific PPAR-δagonist.	price>
R-C-1850	CG347B CAS:1598426-03-9	CG347B is a selective inhibitor of HDAC6.	price>
R-C-1855	THZ2 CAS:1604810-84-5	THZ2,a THZ1 analog,is a selective inhibitor of CDK7 with IC50 of 13.9 nM.THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10nM.	price>

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