Catalog |
name |
Description |
price |
R-R-4822 |
Trimethoprim-d9 CAS No.1189460-62-5 |
Trimethoprim-d9/CAS No.1189460-62-5 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment. |
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R-R-4823 |
Tetroxoprim CAS No.53808-87-0 |
Tetroxoprim/CAS No.53808-87-0 is an antimicrobial DHFR inhibitor. |
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R-R-4824 |
Pyrimethamine-d3 CAS No.1189936-99-9 |
Pyrimethamine-d3/CAS No.1189936-99-9 is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR). |
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R-R-4825 |
Aditoprime CAS No.56066-63-8 |
Aditoprime (Aditoprim)/CAS No.56066-63-8, a selective bacterial dihydrofolate reductase (DHFR) inhibitor, inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime inhibits E.coli and L.casei DHFR with IC50 of 47 and 520 nM, respectively. Aditoprime has a broad antimicrobial spectrum, good antibacterial activity and excellent pharmacokinetics. |
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R-R-4826 |
LY309887 CAS No.127228-54-0 |
LY309887/CAS No.127228-54-0 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity. |
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R-R-4827 |
Calcium N5-methyltetrahydrofolate CAS No.26560-38-3 |
Calcium N5-methyltetrahydrofolate(NSC173328)/CAS No.26560-38-3 is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. |
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R-R-4828 |
Fanotaprim CAS No.2120282-75-7 |
Fanotaprim/CAS No.2120282-75-7 is a dihydrofolate reductase (DHFR) inhibitor with IC50s of 1.57 and 308 nM for tgDHFR (Toxoplasma gondii DHFR) and hDHFR (human DHFR), respectively. Fanotaprim has the potential for the research of toxoplasmosis. |
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R-R-4829 |
Cycloguanil-d6 |
Cycloguanil-d66 is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor. |
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R-R-4830 |
Trimethoprim-d3 CAS No.1189923-38-3 |
Trimethoprim-d3/CAS No.1189923-38-3 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment. |
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R-R-4831 |
Proguanil-d6 hydrochloride |
Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. |
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