Product apis-cell-cycle

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Catalog	name	Description	price
R-C-2623	Y-27632 CAS:146986-50-7	Y-27632 is an orally active,ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300nM,respectively.Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells.Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells.	price>
R-C-2654	Satraplatin CAS:129580-63-8	Satraplatin(JM216,BMS182751)is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy.It has not yet received approval from the U.S.Food and Drug Administration.First mentioned in the medical literature in 1993,satraplatin is the first orally active platinum-based chemotherapeutic drug;other available platinum analogues-cisplatin,carboplatin,and oxaliplatin-must be given intravenously.	price>
R-C-2656	NVP-TNKS656 CAS:1419949-20-4	NVP-TNKS656 is a highly potent,selective,and orally active TNKS2 inhibitor with IC50 of 6nM,and is>300 fold selectivity against PARP1 and PARP2.	price>
R-C-2661	Tasquinimod CAS：254964-60-8	Tasquinimod is an oral antiangiogenic agent,which has the potential for castration-resistant prostate cancer treatment.Tasquinimod binds to the regulatory Zn2+ binding domain of HDAC4 with Kd of 10-30nM.Tasquinimod also is a S100A9 inhibitor.	price>
R-C-2568	Zotiraciclib CAS:1204918-72-8	Zotiraciclib(TG02;SB1317)is a potent inhibitor of CDK2,JAK2,and FLT3 for the treatment of cancer,with IC50s of 13,73,and 56 nM for CDK2,JAK2 and FLT3,respectively.	price>
R-C-2673	Beta-Lapachone CAS:4707-32-8	Beta-Lapachone is a selective DNA topoisomerase I inhibitor,exhibiting no inhibitory activities against DNA topoisomerase II or ligase.	price>
R-C-2674	Floxuridine CAS:50-91-9	Floxuridine(NSC 27640,Deoxyfluorouridine,FUDR)is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo.Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage and apoptosis.Floxuridine has antiviral effects against HSV and CMV.	price>
R-C-2684	RX-3117 CAS：865838-26-2	RX-3117(TV-1360;Fluorocyclopentenylcytosine)is novel a cytidine analog;shows anticancer activity in several cancer cell lines,including gemcitabine-resistant variants.	price>
R-C-2685	LY2334737 CAS：892128-60-8	LY2334737 is an nucleoside analog and is an orally active prodrug of Gemcitabine.LY2334737 exhibits inhibitory activity against enterovirus A71(EV-A71)infection.LY2334737 has antiviral and anticancer effects.	price>
R-C-2693	CCT137690 CAS：1095382-05-0	CCT 137690 is a potent and orally available aurora kinase inhibitor with IC50s of 15,25,and 19nM for aurora A,B and C,respectively.	price>

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