Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00071	Gallic Acid-d2,cas:294660-92-7	Gallic acid-d2(C7H4D2O5,172.1) is intended for use as an internal standard for the quantification of gallic acid by GC- or LC-MS. Gallic acid is a phenol that has been found in C. sinensis and has diverse biological activities.It scavenges DPPH and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM,respectively).Gallic acid (1-100 µM) reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings.	price>
R-XASYS-00072	Gentisein,cas:529-49-7	Gentisein(C13H8O5,244.2) is a xanthone that has been found in H. annulatum and has diverse biological activities.It scavenges DPPH radicals and inhibits the activity of α-glucosidase in cell-free assays (IC50s = 23.3 and 14.7 µM, respectively).	price>
R-XASYS-00073	Glufosinate-d3 (hydrochloride),cas:1323254-05-2	Glufosinate-d3(C5H9D3NO4P·HCl,220.6) is intended for use as an internal standard for the quantification of glufosinate by GC- or LC-MS. Glufosinate is a broad-spectrum herbicide and racemic mixture of L-phosphinothricin, a phytotoxic compound, and D-phosphinothricin, its inactive enantiomer.It is an irreversible inhibitor of glufosinate synthetase 1 (GS1) and GS2 (Kis = 1.1. and 4.8 µM, respectively), enzymes that are required for nitrogen metabolism in plants.	price>
R-XASYS-00074	Gomisin D,cas:60546-10-3	Gomisin D(C28H34O10,530.56) is a lignan that has been found in S. chinensis and has diverse biological activities, including enzyme inhibitory and antioxidant properties.It inhibits acetylcholinesterase (AChE) with an IC50 value of 7.84 ?M.Gomisin D scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl radicals (IC50s = 24.5 and 203 ?M, respectively).	price>
R-XASYS-00075	GPX4 Inhibitor 26a	GPX4 inhibitor 26a(C29H24ClN3O3S,530) is an inhibitor of glutathione peroxidase 4 (GPX4).It inhibits GPX4 activity by 71.7% at 1 µM. GPX4 inhibitor 26a is cytotoxic to 4T1 and MCF-7 breast cancer cells and HT-1080 fibrosarcoma cells (IC50s = 0.78, 6.9, and 0.15 µM, respectively).	price>
R-XASYS-00076	Graphislactone A,cas:52179-44-9	Graphislactone A(C16H14O6,302.3) is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.	price>
R-XASYS-00077	GSK2795039,cas:1415925-18-6	GSK2795039(C23H26N6O2S,450.56) is an inhibitor of NADPH oxidase 2 (NOX2; IC50 = 0.269 ?M). It is selective for NOX2 over NOX1, -3, -4, and -5 (IC50s = >1,000 ?M for all), as well as xanthine oxidase and PKCβ (IC50s = 28.8 and 10 ?M, respectively). GSK2795039 inhibits NOX2-mediated production of reactive oxygen species (ROS) and NADPH depletion in cell-free assays (IC50s = 0.537 and 0.251 ?M, respectively).	price>
R-XASYS-00078	Harmalol (hydrochloride hydrate),cas:6028-00-8	Harmalol(C12H12N2O • HCl [2H2O],272.7) is a β-carboline alkaloid and an active metabolite of harmaline that has been found in P. harmala and has diverse biological activities.It is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A; IC50 = 0.63 µM) and monoamine oxidase A (MAO-A; IC50 = 0.66 µM).It is selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM.	price>
R-XASYS-00079	Hexahydrocurcumin,cas:36062-05-2	Hexahydrocurcumin(C21H26O6,374.43) is a natural product and an active metabolite of curcumin.It reduces prostaglandin E2 (PGE2) production stimulated by phorbol 12-myristate 13-acetate by 37% in human colonic epithelial cells when used at a concentration of 20 ?M. Hexahydrocurcumin (3.125-25 ?M) inhibits overproduction of nitric oxide induced by LPS in RAW 264.7 macrophage cells in a concentration-dependent manner.	price>
R-XASYS-00080	HO-1-IN-1,cas:1093058-52-6	HO-1-IN-1 (Compound 2)(C13H15BrN2,279.18) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM	price>

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