Harmalol (hydrochloride hydrate),cas:6028-00-8

Harmalol(C12H12N2O • HCl [2H2O],272.7) is a β-carboline alkaloid and an active metabolite of harmaline that has been found in P. harmala and has diverse biological activities.It is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A; IC50 = 0.63 µM) and monoamine oxidase A (MAO-A; IC50 = 0.66 µM).It is selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM.

msds of Harmalol