Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00081	HPF,cas:359010-69-8	HPF(C26H16O6,424.4) is a cell-permeable aromatic amino-fluorescein derivative that has little intrinsic fluorescence.It undergoes oxidation only by highly reactive oxygen species (hROS) such as the hydroxyl radical, peroxynitrite, and hROS generated from a peroxidase/H2O2 system. It is inert to hypochlorite ion, nitric oxide, hydrogen peroxide (H2O2), superoxide, and other oxidants. Upon oxidation, HPF is converted to the highly fluorescent molecule fluorescein, with excitation/emission maxima of 490/515 nm, respectively, allowing the simple direct detection of highly reactive biological radicals.	price>
R-XASYS-00083	Indoxyl Sulfate-d5 (potassium salt),cas:1644451-34-2	Indoxyl sulfate-d5(C8HD5NO4S·K,256.3) is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan .It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver.Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay).	price>
R-XASYS-00084	Isochlorogenic acid A,cas:2450-53-5	Isochlorogenic acid A (3,5-Dicaffeoylquinic acid)(C25H24O12,516.45) is a natural phenolic acid with antioxidant and anti-inflammatory activities.	price>
R-XASYS-00085	Isolariciresinol,cas:548-29-8	Isolariciresinol(C20H24O6,360.4) is a lignan that has been found in Cornus officinalis and has diverse biological activities.It scavenges ABTS radicals in a cell-free assay (IC50 = 19.4 µM) and inhibits LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages (IC50 = 84.45 µM).Isolariciresinol (20 µM) inhibits amyloid-β (1-42) self-aggregation in a cell-free assay.	price>
R-XASYS-00086	Isoquercitrin,cas:21637-25-2	Isoquercitrin (Isoquercitroside)(C21H20O12,464.1) is an effective antioxidant and an eosinophilic inflammation suppressor.	price>
R-XASYS-00087	JKE-1716,cas:2421118-05-8	JKE-1716(C20H20Cl2N4O4,451.3) is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210.JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1.	price>
R-XASYS-00088	Kaempferol 3-O-galactoside,cas:23627-87-4	Kaempferol 3-O-galactoside(C21H20O11,448.4) is a flavonoid that has been found in C. vulgaris and has diverse biological activities, including anticancer, antioxidant, and anti-inflammatory properties.It inhibits secretory phospholipase A2 (sPLA2) with an IC50 value of 17.6 µM.Kaempferol 3-O-galactoside (12.5, 25, and 50 µM) decreases protein levels of Akt and induces apoptosis in NCI H460 non-small cell lung cancer (NSCLC) cells.	price>
R-XASYS-00089	Kaempferol 7-neohesperidoside,cas:17353-03-6	Kaempferol 7-neohesperidoside(C27H30O15,594.5) is a flavonoid glycoside that has been found in L. chinensis and has antioxidant and anticancer activities.It scavenges DPPH radicals in a cell-free assay (IC50 = 7.4 µM). Kaempferol 7-neohesperidoside is cytotoxic to A549, HepG2, and HeLa cells (IC50s = 0.53, 0.2, and 0.051 µM, respectively).	price>
R-XASYS-00090	Ketone Ester,cas:1208313-97-6	BD-AcAc2(C8H16O4,176.21) is a ketone ester with anti-obesity and anticonvulsant activities. Oral administration of BD-AcAc2 reduces body weight, food intake, and whole animal adiposity in mice fed an isocaloric diet. BD-AcAc2 increases the seizure threshold and blood levels of β-hydroxybutyrate in a rat model of seizures induced by pentylenetetrazole.	price>
R-XASYS-00091	L-3-n-Butylphthalide, cas:3413-15-8	L-3-n-Butylphthalide(C12H14O2,190.2) is a phthalide that has been found in A. graveolens and has antiplatelet and neuroprotective activities.It inhibits ADP-, collagen-, and arachidonic acid-induced platelet aggregation ex vivo when administered at doses ranging from 3 to 100 mg/kg and inhibits thrombus formation in a collagen and epinephrine-induced rat model of experimental thrombosis.	price>

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