Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00061	Diosmetin-d3,cas:1189728-54-8	Diosmetin-d3(C16H9D3O6,303.3) is intended for use as an internal standard for the quantification of diosmetin by GC- or LC-MS. Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH in a concentration-dependent manner.	price>
R-XASYS-00062	Diphenyleneiodonium chloride,cas:4673-26-1	Diphenyleneiodonium (DPI) chloride (DPIC)(C12H8ClI,314.55), as a NADH/NADPH oxidase inhibitor, has possessing potent antimicrobial activity against Mtb and S. aureus	price>
R-XASYS-00063	Diquat (bromide),cas:85-00-7	Diquat(C12H12N2.2Br,344) is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).Diquat administration has been used to induce oxidative stress in vitro and in animal models.It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.	price>
R-XASYS-00064	DMNQ,cas:6956-96-3	DMNQ(C12H10O4,218.2) is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation. The amount of oxidative stress is proportional to the amount of DMNQ applied and can alter diverse cellular parameters, including signal transduction, mitochondrial function, and gene expression.	price>
R-XASYS-00065	DPPP,cas:110231-30-6	DPPP(C28H19P,386.4) is a probe that reacts stoichiometrically with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). Plasma levels of lipid hydroperoxides of phosphatidylcholine, phosphatidylethanolamine, triglycerides, and cholesteryl esters have been measured by HPLC with a post column detection system using DPPP.	price>
R-XASYS-00066	EMPO,cas:61856-99-3	EMPO(C8H13NO3,171.2) is a hydrophilic cyclic nitrone analog of the free radical spin trap DMPO . The EMPO-superoxide adduct (EMPO-OOH) exhibits an ESR spectrum that is similar to the DMPO-OOH spectrum.	price>
R-XASYS-00067	Euparin,532-48-9	Euparin(C13H12O3,216.23) exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to cells up to the first twenty minutes after infection.	price>
R-XASYS-00068	Ferrichrome (iron-free),cas:34787-28-5	Ferrichrome(C27H45N9O12,687.7) is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be utilized as a heterologous siderophore by bacteria, including P. aeruginosa and V. parahaemolyticus. Ferrichrome (0.8 μM) inhibits proliferation of murine spleen mononuclear cells induced by concanavalin A and reduces the number of concanavalin A-stimulated CD4+ T cells expressing the IL-2 receptor.	price>
R-XASYS-00069	Fisetin-d5	Fisetin-d5(C15H5D5O6,291.3) is intended for use as an internal standard for the quantification of fisetin by GC- or LC-MS. Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities.It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-Formyl-Met-Leu-Phe in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM.	price>
R-XASYS-00070	G6PDi-1,cas:2457232-14-1	G6PDi-1(C14H12N4OS,284.3) is a reversible and noncompetitive inhibitor of glucose-6-phosphate dehydrogenase (G6PDH; IC50 = 0.07 µM), the enzyme that converts G6P to 6-phosphogluconolactone using NADP+ as a cofactor in the first step of the pentose phosphate pathway.	price>

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