Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00102	Malabaricone B,cas:63335-24-0	Malabaricone B(C21H26O4,342.4) is a diarylnonanoid that has been found in Myristica and has diverse biological activities, including enzyme inhibitory, antimicrobial, anticancer, and antioxidant properties.It is an inhibitor of sphingomyelin synthase 1 and -2 (IC50s = 3.5 and 2.5 μM, respectively, in fibroblast cell lysates).It is active against the bacteria S. aureus, B. subtilis, and S. durans (MIC = 1 μg/ml for all) and three strains of the fungus C. albicans (MICs = 4-16 μg/ml).	price>
R-XASYS-00103	Malabaricone C,cas:63335-25-1	Malabaricone C(C21H26O5,358.4) is a diarylnonanoid that has been found in Myristica and has diverse biological activities.It scavenges 59.9% of 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 7 μg/ml.Malabaricone C is active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml).It is cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively).	price>
R-XASYS-00104	Meglutol-d3,cas:59060-36-5	Meglutol-d3(C6H7D3O5,165.2) is intended for use as an internal standard for the quantification of meglutol by GC- or LC-MS. Meglutol is an HMG-CoA reductase inhibitor (IC50 = 4 nM) and antimetabolite of mevalonic acid.Dietary administration of meglutol (10, 20, and 30 mg/kg per day) reduces serum total cholesterol levels in normal rats, as well as reduces them in high-cholesterol fed and hypercholesterolemic rats when administered in the drinking water at a dose of 50 mg/kg per day.	price>
R-XASYS-00105	Melittoside,cas:19467-03-9	Melittoside(C21H32O15,524.47) is an iridoid glycoside that has been found in S. trojana and has antioxidant and enzyme inhibitory activities.It scavenges free radicals in a Trolox equivalent antioxidant capacity (TEAC) assay.Melittoside also inhibits the activity of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) by 24.6 and 12.8%, respectively, when used at a concentration of 250 ?g/ml in a cell-free assay.	price>
R-XASYS-00106	Methazolamide-d6,cas:1795142-30-1	Methazolamide-d6(C5H2D6N4O3S2,242.3) is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM).It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg.	price>
R-XASYS-00107	Methoxy-PMS (1-Methoxy PMS),cas:65162-13-2	1-methoxy-5-Methylphenazinium (methyl sulfate)(C15H16N2O5S,336.36) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes.It can be used to visualize NAD-linked dehydrogenase activities.	price>
R-XASYS-00108	Methyl 3,4-Dihydroxyphenylacetate,cas:25379-88-8	Methyl 3,4-dihydroxyphenylacetate(C9H10O4,182.2) is a polyphenol that has been found in I. aquifolium seeds and has antioxidant and antiviral activities.It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 0.0025 mg/ml).Methyl 3,4-dihydroxyphenylacetate (0.01 µg/ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.	price>
R-XASYS-00109	MGR1,cas:2361529-46-4	MGR1(C22H24O5,368.4) is a probe that generates reactive oxygen species (ROS).Upon activation by esterases, MGR1 produces superoxide in vitro, an effect that is reversed by superoxide dismutase (SOD). MGR1 produces ROS and increases production of oxidized phosphatidylserine species in HEK293T cells.	price>
R-XASYS-00110	MHY553,cas:6265-56-1	MHY553(C13H9NO2S,243.3) is an agonist of peroxisome proliferator-activated receptor α (PPARα).It activates PPARα in HepG2 cells in a reporter assay when used at a concentration of 1 µM but does not activate PPARβ or PPARγ at 10 µM. MHY553 (3 µM) prevents triglyceride accumulation induced by the liver X receptor (LXR) agonist T0901317 in HepG2 cells, as well as scavenges reactive oxygen species (ROS) and peroxynitrite in cell-free assays (IC50s = 39.7 and 2.39 µM, respectively)	price>
R-XASYS-00111	MHY908,cas:1393371-39-5	MHY908 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ that increases transcriptional activity of PPARα and PPARγ in a luciferase reporter assay in AC2F rat liver cells when used at a concentration of 5 µM.	price>

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