Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00112	MitoB,cas:1247025-84-8	MitoB(C25H23BO2P•Br,477.1) is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce a phenol product, MitoP.	price>
R-XASYS-00113	MitoPQ,cas:1821370-28-8	MitoPQ(C39H46N2P • 3I,954.5) is comprised of a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.Driven by membrane potential, it accumulates selectively in the mitochondrial matrix where it produces superoxide by redox cycling at the flavin site of complex I.	price>
R-XASYS-00114	Mitoquinol,cas:845959-55-9	Mitoquinol(C37H46O4P•CH3O3S,680.8) is a ubiquinone derivative that specifically accumulates in mitochondria due to the covalent attachment of the cation triphenylphosphonium. It functions as an antioxidant, preventing lipid peroxidation-induced apoptosis and protecting mitochondria from oxidative damage.	price>
R-XASYS-00115	Mitoquinol-d15	Mitoquinol-d15(C37H31D15O4P·CH3O3S, 695.9) is intended for use as an internal standard for the quantification of mitoquinol by GC- or LC-MS. Mitoquinol is a mitochondria-targeted antioxidant and reduced form of mitoquinone .It reduces hydrogen peroxide production in succinate-fueled isolated bovine aortic endothelial mitochondria.	price>
R-XASYS-00116	Mitoquinone mesylate (Mitoquinone methanesulfonate),cas:845959-50-4	Mitoquinone mesylate (Mitoquinone methanesulfonate)(C38H47O7PS,678.81) is among the widely used antioxidants that target the mitochondria. It was developed to readily penetrate the BBB and neuronal membranes, where it is concentrated into several hundred-folds within the mitochondria where it mediates the local anti-oxidative capacity	price>
R-XASYS-00117	N-acetyl-5-Aminosalicylic Acid,cas:51-59-2	N-acetyl-5-Aminosalicylic acid(C9H9NO4,195.2) is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases. It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM. N-acetyl-5-Aminosalicylic acid (100 µM) scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by hydroxy radicals.	price>
R-XASYS-00118	N-acetyl-L-Cysteine amide,cas:38520-57-9	N-acetyl-L-Cysteine amide (NACA)(C5H10N2O2S,162.2) is a novel antioxidant, the amide form of N-acetylcysteine (NAC), due to its permeability through both cellular and mitochondrial membranes.N-acetylcysteine amide permeates cellular and mitochondrial membranes, crosses the blood-brain barrier [1,2] and has higher radical scavenging ability, metal chelating activity and reducing power than NAC.	price>
R-XASYS-00119	NXY-059,cas:168021-79-2	Disufenton sodium (NXY-059)(C11H13NNa2O7S2,381.33) is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone(PBN), both NXY-059, its parent PBN and their hydrolysis/oxidation product MNT are very powerful scavengers of free radicals. IC50 value:Target: Neuroprotectantin vitro: Disufenton sodium is more soluble than the spin trapping agent α-phenyl-N-tert-butyl nitrone (PBN).	price>
R-XASYS-00120	Orsellinic Acid,cas:480-64-8	Orsellinic acid(C8H8O4,168.2) is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals with an IC50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.	price>
R-XASYS-00121	Palmarumycin C3,cas:159934-11-9	Palmarumycin C3(C20H12O6,348.3) is a spirobisnaphthalene fungal metabolite that has been found in C. palmarum and has diverse biological activities.It is active against the bacteria A. tumefaciens, B. subtilis, P. lachrymans, R. solanacearum, S. haemolyticus, and X. vesicatoria.	price>

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