Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00132	Pyranonigrin A,cas:773855-65-5	Pyranonigrin A(C10H9NO5,223.2) is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).	price>
R-XASYS-00133	RC363,cas:2584411-86-7	RC363(C18H24OS2,320.5) is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .It reduces 2,2-diphenyl-1-picrylhydrazyl radicals by approximately 40% in a cell-free assay when used at a concentration of 25 µM.	price>
R-XASYS-00134	RC574,cas:2584411-87-8	RC574(C18H24OSSe,367.4) is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol.It inhibits glutamate-induced cell death in HT22 cells (IC50 = 276.2 nM) and mouse primary cortical neurons when used at a concentration of 3 μM. RC574 (3 μM) increases glutathione peroxidase 1 (GPX1) levels and GPX activity, as well as inhibits glutamate-induced mitochondrial superoxide anion production, in HT22 cells.	price>
R-XASYS-00135	Reuterin,cas:2134-29-4	Reuterin(C3H6O2,74.1) is a glycerol metabolite originally isolated from L. reuteri, a bacteria found in the intestines of humans, that has antibacterial activity.It is produced by L. reuteri during exposure to live or UV-killed E. coli.Reuterin is active against E. coli and several species of Bacteroides, Bifidobacterium, and Eubacterium (MICs = 1.9-15 mM) as well as C. difficile and B. vulgatus (MICs = <1.9 mM for both).	price>
R-XASYS-00136	Reynoutrin,cas:549-32-6	Quercetin 3-O-β-D-xylopyranoside(C20H18O11,434.35) is a flavonoid glycoside that has been found in N. candida and has diverse biological activities.It reduces malondialdehyde (MDA) levels in isolated rat brain when used at a concentration of 10 ?g/ml.Quercetin 3-O-β-D-xylopyranoside (10, 50, and 100 ?g/ml) reduces LPS- and cerulein-induced increases in reactive oxygen species (ROS) production and levels of GRP78, a marker of endoplasmic reticulum stress, in an AR42J rat pancreatic acinar cell model of pancreatitis	price>
R-XASYS-00137	S1QEL1.1,cas:897613-29-5	S1QEL1.1(C23H24N4O3S,436.5) is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart.	price>
R-XASYS-00138	Satratoxin H,cas:53126-64-0	Satratoxin H(C29H36O9,528.6) is a trichothecene mycotoxin that has been found in Stachybotrys.1 It induces production of reactive oxygen species (ROS), increases in malondialdehyde (MDA) levels, and induces apoptosis in PC12 cells when used at concentrations ranging from 5 to 100 nM. Satratoxin H is cytotoxic to human umbilical vein endothelial cells.	price>
R-XASYS-00139	Sekikaic Acid,cas:607-11-4	Sekikaic acid(C22H26O8,418.4) is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities.It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µM.	price>
R-XASYS-00140	Sinapine thiocyanate,cas:7431-77-8	Sinapine thiocyanate(C17H24N2O5S,368.45) is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.	price>
R-XASYS-00141	SOTS-1 (technical grade),cas:223507-96-8	Superoxide radical anion(C16H14N2O6,330.3) is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate.	price>

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