Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00142	SRS11-92,cas:1467047-25-1	SRS11-92(C22H28N2O2,352.5) is a ferroptosis inhibitor and a derivative of ferrostatin-1 . It inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM). SRS11-92 (2 µM) inhibits iron-induced cell death in isolated mouse kidney proximal tubules, and fully protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia when used at a concentration of 100 nM.	price>
R-XASYS-00143	Stobadine,cas:85202-17-1	Stobadine(C13H18N2,202.3) is a pyridoindole antioxidant.It scavenges hydroxyl, peroxyl, and alkoxyl radicals and quenches singlet oxygen in cell-free assays. Ex vivo, stobadine (2 mg/kg) reduces lipid peroxidation induced by hypoxia and reoxygenation in rat forebrain.It improves survival in a rat model of carotid artery ligation-induced cerebral ischemia.	price>
R-XASYS-00144	Succinobucol (AGI-1067),cas:216167-82-7	Succinobucol(C35H52O5S2,616.91) is a metabolically stable derivative of probucol with diverse biological activities.It inhibits hydrogen peroxide-induced oxidation of the redox-sensitive dye H2DCF in human pulmonary artery endothelial cells (HPAECs) and U937 cells when used at concentrations of 5 and 10 ?M.Succinobucol (0.3-10 ?M) reduces LPS-induced production of IL-6, IL-1β, and TNF-α in peripheral blood mononuclear cells (PBMCs)	price>
R-XASYS-00145	Sydowinin B,cas:58450-00-3	Sydowinin B(C16H12O7,316.3) is a xanthone polyketide that has been found in A. sydowii and has immunosuppressant activity.It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 µg/ml, respectively).	price>
R-XASYS-00146	TAN 420E,cas:91700-93-5	TAN 420E(C30H44N2O9,576.7) is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml.	price>
R-XASYS-00147	Taurine-d4,cas:342611-14-7	Taurine-d4(C2H3D4NO3S,129.2) is intended for use as an internal standard for the quantification of taurine by GC- or LC-MS. Taurine is a sulfur-containing amino acid produced endogenously and also ingested in the diet.It is ubiquitously present in most cells and has diverse biological activities, including antioxidative, anticancer, cardioprotective, and neuroprotective properties	price>
R-XASYS-00148	Theobromine-d6,cas:117490-40-1	Theobromine-d6(C7H2D6N4O2,186.2) is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities.It is an adenosine A1 receptor antagonist (IC50s = 200-280 μM in radioligand binding assays using rat brain membranes)	price>
R-XASYS-00149	Thymohydroquinone,cas:2217-60-9	Thymohydroquinone(C10H14O2,166.2) is a quinone that has been found in N. sativa seeds and has diverse biological activities.It scavenges 2,2-diphenyl-1-picrylhydrazyl free radicals in a cell-free assay (IC50 = 2.4 μg/ml) and has a Trolox equivalent value of 2.6 in an oxygen radical absorbance capacity (ORAC) assay when used at concentrations ranging from 1.6 to 6.4 μg/ml.	price>
R-XASYS-00150	Tiopronin-d3,cas:1189700-74-0	Tiopronin-d3(C5H6D3NO3S,166.2) is intended for use as an internal standard for the quantification of tiopronin by GC- or LC-MS. Tiopronin is an antioxidant that has diverse biological activities.It reduces free radical production by murine macrophages and granulocytes in vitro in a dose-dependent manner.Tiopronin induces expression of hypoxia-inducible factor 1α (HIF-1α) and increases VEGF secretion in human colon carcinoma cells.	price>
R-XASYS-00151	trans-Resveratrol-d4,cas:1089051-56-8	trans-Resveratrol-d4(C14H8D4O3,232.3) is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-MS. trans-Resveratrol is a polyphenolic phytoalexin found in a variety of plants, including grapes, that has anti-inflammatory, antioxidant, and anticancer activities.It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 μM, respectively), but not COX-2 (EC50s = >100 μM and 85 μM, respectively).	price>

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