Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00162	Zinc Protoporphyrin,cas:15442-64-5	Zinc Protophorin (Zn (II) - protophorin IX)(C34H32N4O4Zn,626.02) is a competitive inhibitor of heme oxygenase-1 (HO-1) with oral activity, significantly reducing the protective effect of phloroglucinol (PG) on H2O2. Zinc Protophyrin can be used as a screening marker for iron deficiency in individual pregnant women and children, as well as to assess the combination of iron status and hemoglobin concentration in the population. Zinc Protophoryrin has anticancer activity.	price>
R-XASYS-00163	2-Methoxyestradiol,cas:362-07-2	2-Methoxyestradiol (2-ME2), 17 with oral activity β- The endogenous metabolite of estradiol (E2), which is an inducer of apoptosis and an inhibitor of angiogenesis, has effective anti-tumor activity. 2-Method estradiol can also destabilize microtubules. 2-Methoxyestradiol is an effective superoxide dismutase (SOD) inhibitor and reactive oxygen species generator that can induce autophagy in transformed cell lines HEK293, cancer cell lines U87, and HeLa.	price>
R-XASYS-00165	Lycopene,cas:502-65-8	Lycopene is an open chain unsaturated carotenoid that gives tomatoes, guava, rose hip, watermelon and pink grapefruit its red color. Studies show that lycopene intake is significantly associated with lower risk of lung, colon and stomach carcinogenesis. It is an antioxidant.	price>
R-XASYS-00166	Asiaticoside,cas:16830-15-2	Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns, due to its significant healing capacity. Asiaticoside is the main constituent of C. asiatica, which has been used historically in the Ayurvedic system to treat a variety of health issu	price>
R-XASYS-00167	Nobiletin,cas:478-01-3	Nobiletin is a flavanoid with antioxidant and anti-inflammatory properties found in the rind of tangerines. The compound has been observed to inhibit the phosphorylation of MEK (mitogen-activated protein kinase).	price>
R-XASYS-00168	Hesperidin,cas:520-26-3	Hesperidin is a flavonoid which has been found to be a potent chemopreventive agent in oral, urinary bladder, and colon carcinogenesis in animal models.	price>
R-XASYS-00169	D-α-Hydroxyglutaric acid disodium,cas:103404-90-6	D- α- Hydroglutaric acid disodium (disodium (R) - 2-hydroxyglutarate) is a major metabolite accumulated in the neurometabolic disease D-2-hydroxyglutaric aciduria. D- α- Hydroxyglutaric acid disodium is α- Ketoglutaric acid（ α- KG), which can inhibit a variety of α- KG dependent dioxygenases, Ki 10.87 mM. D- α- Hydroxyglutaric acid disodium can increase the production of reactive oxygen species (ROS).	price>
R-XASYS-00170	Succinyl phosphonate trisodium salt,cas:864167-45-3	Succinyl phosphonate trisodium salt(C4H4Na3O6P,248.01) is α- Ketoglutarate dehydrogenase (KGDHC) inhibitors can effectively inhibit KGDHC in muscle, bacteria, brain, and human fibroblasts. Succinyl phosphonate trisodium salt inhibits 2-oxoglutarate dehydrogenase (OGDH) and impairs the activity of cancer cells in a cell specific metabolic dependent manner.	price>
R-XASYS-00172	CORM-401,cas:1001015-18-4	CORM-401(C8H6MnNO6S2,331.20) is a CO releasing molecule sensitive to oxidants. CORM-401 induces an increase in NO in endothelial calcium signaling regulation. CORM-401 reduces TNF- α/ CHX and H2O2 induced ROS production. CORM-401 decouples mitochondrial respiration and inhibits glycolysis.	price>
R-XASYS-00173	Isobavachalcone,cas:20784-50-3	Isobavicalcone (Corylifolinin)(C20H20O4,324.37), derived from Psoralea corylifolia, is an effective inhibitor of Akt signaling pathway that can induce apoptosis in human cancer cells (with an IC50 value of 7.92 μ M inhibits the growth of OVCAR-8 cancer cells) and has anticancer and antiproliferative activities. Isobavicalcone can also induce the production of reactive oxygen species in OVCAR-8 cells.	price>

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