Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00186	L67,cas:325970-71-6	L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC50 are 10 μM). L67 (DNA Ligase Inhibitor) can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS.	price>
R-XASYS-00187	W-54011,cas:405098-33-1	W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM	price>
R-XASYS-00188	Daphnetin,cas:486-35-1	Daphnetin (7,8-dihydroxycoumarin) is a coumarin derivative that can be derived from Genus Daphne and is an orally effective protein kinase inhibitor with an IC50 value of 7.67 for EGFR, PKA, and PKC, respectively μ M、9.33 μ M and 25.01 μ M。 Daphnetin triggers reactive oxygen species induced apoptosis and induces cytoprotective autophagy by regulating the AMPK/Akt/mTOR pathway.	price>
R-XASYS-00189	Urolithin C,cas:165393-06-6	Urolithin C, a polyphenolic intestinal microbial metabolite of ellagic acid, is a glucose dependent activator of insulin secretion. Urolithin C is an L-type Ca2+channel opener that enhances Ca2+influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondrial mediated pathways	price>
R-XASYS-00190	Garcinone D,cas:107390-08-9	Garcinone D is a natural xanthone from bamboo, which can promote the proliferation of C17.2 neural stem cells. Garcinone D increases phosphorylation signal transducer and transcriptional activator 3 (p-STAT3), Cyclin D1, and nuclear factor erythrocyte 2 related factor (Nrf2), and heme oxygenase-1 (HO-1) protein levels in a concentration and time dependent manner.	price>
R-XASYS-00191	Aurothioglucose,cas:12192-57-3	Aurothiolucose (Gold thiolucose) contains monovalent gold ions and is an effective inhibitor of the active site of TrxR1 (thioredoxin reductase 1) with an IC50 of 65 nM. Aurothioglucose inhibits NF in vitro- κ DNA binding of B. Aurothioglucose has anti HIV and anti rheumatic activities.	price>
R-XASYS-00192	Epiberberine chloride,cas:889665-86-5	Epiberberine chloride is an alkaloid obtained from Coptis chinensis. It is an effective AChE and BChE inhibitor, and a non competitive BACE1 inhibitor with IC50 values of 1.07, 6.03, and 8.55, respectively μM.Epiberberine chloride has an antioxidant effect and can clear ONOO - (IC50, 16.83 μM) It can be used in the research of Alzheimers disease and diabetes.	price>
R-XASYS-00193	N-tert-Butyl-α-phenylnitrone,cas:3376-24-7	N-tert-Butyl- α- Phenylnitrone is a nitrone-based free radical scavenger that can form nitric oxide spin adducts. N-tert-Butyl- α- Phenylnitrone inhibits the catalytic activity of COX2. N-tert-Butyl- α- Phenylnitrone has effective ROS clearance, anti-inflammatory, neuroprotective, anti-aging and anti diabetes effects, and can penetrate the blood brain barrier.	price>
R-XASYS-00194	CL097,cas:1026249-18-2	CL097 is an effective TLR7 and TLR8 agonist that can induce proinflammatory cytokines in macrophages. CL097 induces NADPH oxidase activation, leading to an increase in fMLF stimulated ROS production.	price>
R-XASYS-00195	11-oxo-mogroside V,cas:126105-11-1	11-oxo-mogroside V(C60H100O29,1285.42) is a natural sweetener with strong antioxidant activity. 11-oxo-mogroside V has a significant inhibitory effect on active oxygen species, acting on O2 -, H2O2, and * OH, with an EC50 of 4.79, 16.52, and 146.17, respectively μ g/mL	price>

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