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Home > products > fluorescent-dyes > No-ROS-Rox-derivatives > gsk2795039

GSK2795039,cas:1415925-18-6

N-[3-(2,3-dihydro-1-methyl-1H-indol-6-yl)-1-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1H-pyrazole-3-sulfonamide

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-XASYS-00077 10mg 535.00
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R-XASYS-00077 50mg 1615.00
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Product description

GSK2795039(C23H26N6O2S,450.56) is an inhibitor of NADPH oxidase 2 (NOX2; IC50 = 0.269 ?M). It is selective for NOX2 over NOX1, -3, -4, and -5 (IC50s = >1,000 ?M for all), as well as xanthine oxidase and PKCβ (IC50s = 28.8 and 10 ?M, respectively). GSK2795039 inhibits NOX2-mediated production of reactive oxygen species (ROS) and NADPH depletion in cell-free assays (IC50s = 0.537 and 0.251 ?M, respectively).

GSK2795039,cas:1415925-18-6

Appearance N/A
Molecular Weight N/A
Purity >90%
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 1 year
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msds of GSK2795039
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