Product fluorescent-dyes-No-ROS-Rox-derivatives

Home > products > fluorescent-dyes> No-ROS-Rox-derivatives

Catalog	name	Description	price
R-XASYS-00336	Methylprotodioscin,cas:54522-52-0	Methylprotodioscin(C52H86O22,1063.2) is a steroidal saponin that has been found in A. cochinchinensis and has diverse biological activities.It suppresses mucin 5AC (MUC5AC) production induced by EGF or phorbol 12-myristate 13-acetate (PMA) in H292 cells when used at a concentration of 1 µM.1 Methylprotodioscin inhibits the proliferation of HeLa cervical cancer cells.	price>
R-XASYS-00337	Ginsenoside Rf,cas:52286-58-5	Ginsenoside Rf(C42H72O14,801.0) is a steroid glycoside found in plants of the genus Panax that has diverse biological activities.It inhibits production of IL-1β, IL-6, TNF-α, NO, and reactive oxygen species (ROS) in human HT-29 intestinal epithelial cells and RAW 264.7 mouse macrophages in a dose-dependent manner. Ginsenoside Rf inhibits N-type calcium channels in rat sensory neurons (IC50 = 40μM).	price>
R-XASYS-00338	2,3,5,4-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucoside,cas:82373-94-2	2,3,5,4-Tetrahydroxyl-diphenylethylene 2-O-β-D-glucoside (TSG)(C20H22O9,406.4) is a stilbene glucoside that has been found in P. multiflorum and has diverse biological activities.It scavenges DPPH radicals in a cell-free assay (IC50 = 40 µM).	price>
R-XASYS-00339	Arecaidine propargyl ester (hydrobromide),cas:116511-28-5	Arecaidine propargyl ester(C10H13NO2•HBr,260.1) is an agonist of M2 muscarinic acetylcholine receptors (mAChRs).It selectively binds to M2 over M1, M3, M4, and M5 mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 µM, respectively).	price>
R-XASYS-00340	CAY10735,cas:2251753-58-7	CAY10735(C44H60FN3O4,714.0) is an anticancer compound.It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56μM). CAY10735 inhibits migration of and the epithelial-to-mesenchymal transition (EMT) in A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner.	price>
R-XASYS-00342	Buformin (hydrochloride),cas:1190-53-0	Buformin(C6H15N5•HCl,193.7) is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis.	price>
R-XASYS-00343	Chebulic Acid,cas:23725-05-5	Chebulic acid(C14H12O11,356.2) is a phenol that has been found in T. chebular and has diverse biological activities.It reduces production of reactive oxygen species (ROS) in human umbilical vein endothelial cells (HUVECs) induced by glyceraldehyde-related advanced glycation end products (glycer-AGEs) when used at a concentration of 100 µg/ml.	price>
R-XASYS-00344	Lithospermic Acid,cas:28831-65-4	Lithospermic acid(C27H22O12,538.5) is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities.It inhibits xanthine oxidase (IC50 = 5.2 µg/ml) and scavenges DPPH radicals in cell-free assays (IC50 = 23.2 µg/ml).	price>
R-XASYS-00345	Taraxasterol Acetate,cas:6426-43-3	Taraxasterol acetate(C32H52O2,468.8) is a pentacyclic triterpene that has been found in P. sagittalis and has diverse biological activities.It reduces the production of reactive oxygen species (ROS) and Hsp72 induced by phorbol 12-myristate 13-acetate (PMA） in isolated human neutrophils when used at concentrations of 10 and 100 µM and increases Hsp72 production in unstimulated isolated human neutrophils at 100 µM.	price>
R-R-0345	(S,R,S)-AHPC-Me hydrochloride	(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.	price>

...