Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00356	Miltirone,cas:27210-57-7	Miltirone(C19H22O2,cas:282.4) is a tanshinone that has been found in S. miltiorrhiza and has diverse biological activities.It protects lard from thermal oxidation when used at a concentration of 0.02%.Miltirone is a partial agonist of the benzodiazepine receptor (IC50 = 0.3 µM).	price>
R-XASYS-00357	Verbenalin,cas:548-37-8	Verbenalin(C17H24O10,388.4) is an iridoid glucoside that has been found in V. officinalis and has diverse biological activities.It inhibits the activities of COX-1 and COX-2 by 37 and 48%, respectively, when used at a concentration of 258 µM.Verbenalin (129 µM) inhibits proliferation of AGS gastric, SF-268 CNS, HCT116 colon, NCI H460 lung, and MCF-7 breast cancer cells.	price>
R-XASYS-00358	ZZW-115,cas:10122-45-9	ZZW-115(C24H31F3N4S•3HCl,574.0) is an inhibitor of nuclear protein 1 (NUPR1).It binds to NUPR1 (Kd = 2.1 µM) in a cell-free assay. ZZW-115 is cytotoxic against a panel of 11 pancreatic ductal adenocarcinoma cell lines (IC50s = 0.84-4.93 µM), as well as against a panel of 16 additional cancer cell lines, including glioblastoma, lymphoma, and leukemia cells (IC50s =0.25-7.75 µM).	price>
R-XASYS-00359	Periplogenin,cas:514-39-6	Periplogenin(C23H34O5,390.5) is a cardenolide and an active metabolite of periplocin that has been found in P. graeca and has diverse biological activities.It reduces the activity of porcine Na+/K+ ATPase when used at concentrations of 0.3 or 0.6 µM.Periplogenin induces apoptosis in U937 and PC3 prostate cancer cells, as well as inhibits the proliferation of these cells (EC50s = 1.41 and 1.2 µM, respectively), when used at concentrations of 0.1 or 0.2 µM.	price>
R-XASYS-00360	Hederagenin,cas:465-99-6	Hederagenin(C30H48O4,472.7) is a triterpene saponin that has been found in P. eximia with diverse biological activities.It increases production of reactive oxygen species (ROS), reduces colony formation, and induces apoptosis in cisplatin-resistant head and neck carcinoma (HNC) cells.	price>
R-XASYS-00361	Glutathione ethyl ester,cas:92614-59-0	Glutathione (GSH) ethyl ester(C12H21N3O6S,335.4) is a cell-permeable derivative of GSH,a nucleophilic co-substrate to glutathione transferases.It increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells when used at a concentration of 10 mM.2 GSH ethyl ester (10 mM) decreases reactive oxygen species (ROS) levels and TNF-α-induced IL-8 secretion in IB3-1 cells.	price>
R-XASYS-00362	Hispidin,cas:555-55-5	Hispidin(C13H10O5,246.2) is a polyphenol originally isolated from P. hispidus that has diverse biological activities, including antioxidant, anti-inflammatory, and cytoprotective properties.In a trolox equivalent antioxidant capacity (TEAC) assay, hispidin scavenges radicals at 14.47 equivalents of trolox.	price>
R-XASYS-00363	DAz-1,cas:1112977-84-0	DAz-1(C10H14N4O3,238.2) is a cell-permeable chemical probe that reacts specifically with sulfenic acid-modified proteins.The azido group of DAz-1 provides a method for selective conjugation to phosphine- or alkynyl- derivatized reagents, such as biotin or various fluorophores, for subsequent analysis of the labeled proteins.	price>
R-XASYS-00364	Alloisolithocholic Acid,cas:2276-93-9	Alloisolithocholic acid(C24H40O3,376.6) is a metabolite of the secondary bile acid metabolite 3-oxo lithocholic acid (dehydrolithocholic acid).It is formed from 3-oxo lithocholic acid by gut microbiota.Alloisolithocholic acid (20 µM) increases the association of the nuclear hormone receptor nerve growth factor IB (Nr4a1) to the gene encoding forkhead box protein P3 (Foxp3) in isolated mouse CD4+ T cells.	price>
R-XASYS-00365	Echinacoside,cas:82854-37-3	Echinacoside(C35H46O20,786.7) is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities.It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals (EC50 = 6.6 µM in a cell-free assay).Echinacoside (10 µg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells.	price>

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