Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00346	T-2 Toxin,cas:21259-20-1	T-2 toxin(C24H34O9,466.6) is a trichothecene mycotoxin that has been found in Fusarium.1 It binds to and inhibits peptidyltransferase in the 60S ribosomal subunit, inducing a ribotoxic stress response that triggers JNK and p38 MAPK signaling. T-2 toxin (3 nM) decreases toll-like receptor expression and LPS-induced production of IL-1β.	price>
R-XASYS-00347	Didymin,cas:14259-47-3	Didymin(C28H34O14,594.6) is a flavonoid that has been found in citrus fruits with diverse biological activities.It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cell death and increases superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) activity in SH-SY5Y cells differentiated into a neuronal phenotype.	price>
R-XASYS-00348	Bacopaside II,cas:382146-66-9	Bacopaside II is a triterpene glycoside found in B. monnieri that has neuroprotective, anti-angiogenic, and anticancer activities.Bacopaside II (0.4 mg/ml) decreases hydrogen peroxide-induced intracellular reactive oxygen species (ROS) production and cell death in N2a neuroblastoma cells.	price>
R-XASYS-00349	Atpenin A5,cas:119509-24-9	Atpenin A5(C15H21Cl2NO5,366.2), an antifungal antibiotic isolated from Penicillium sp. found in soil, is a highly specific ubiquinone-binding site inhibitor of succinate dehydrogenase (IC50s = 12 and 3.7 nM in nematode and mammalian mitochondria, respectively, versus IC50s > 100 μM for inhibition of complex I and complex III enzymes).	price>
R-XASYS-00350	20(R)-Ginsenoside Rh2,cas:112246-15-8	20(R)-Ginsenoside Rh2(C36H62O8,622.9) is a steroid glycoside originally isolated from P. ginseng and an isomer of 20(S)-ginsenoside Rh2 that has diverse biological activities.It inhibits the replication of murine gammaherpes virus 68 (MHV-68; IC50 = 2.77 μM) and the lytic replication of human gammaherpes virus in BC3 cells.	price>
R-XASYS-00351	DC_AC50,cas:497061-48-0	DC_AC50(C17H12BrF2N3OS,424.3) is an inhibitor of the copper-trafficking proteins Atox1 and CCS.It binds to purified Atox1 and CCS (Kds = 6.8 and 8.2 μM, respectively) and inhibits the interaction between Atox1 and domain 4 of the Cu+-ATPase ATP7B in the presence of zinc in a FRET-based assay when used at a concentration of 100 μM.	price>
R-XASYS-00352	NSC 109555,cas:15427-93-7	NSC 109555(C19H24N10O•2CH3SO3H,600.7) is an ATP-competitive inhibitor of checkpoint kinase 2 (Chk2; IC50 = 200 nM in a cell-free kinase assay).It is selective for Chk2 over Chk1 and 16 kinases in a panel but does inhibit Brk, c-Met, IGFR, and LCK with IC50 values of 210, 6,000, 7,400, and 7,100 nM, respectively. NSC 109555 inhibits Chk2 autophosphorylation and phosphorylation of the Chk2 substrate histone H1 in vitro (IC50 = 240 nM).	price>
R-XASYS-00353	Polygalasaponin F,cas:882664-74-6	Polygalasaponin F is a triterpenoid saponin originally isolated from Polygala japonica and has diverse biological activities.It inhibits LPS-induced increases in TNF-α and nitric oxide (NO) production, inducible nitric oxide synthase (iNOS) levels, and nuclear translocation of NF-κB p65 in BV-2 microglia when used at concentrations of 0.1, 1, and 10 μM.	price>
R-XASYS-00354	Isoverbascoside,cas:61303-13-7	Isoverbascoside(C29H36O15,624.6) is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities.It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml.	price>
R-XASYS-00355	Trilobatin,cas:4192-90-9	Trilobatin(C21H24O10,436.4) is a dihydrochalcone glucoside and derivative of phloretin (Item No. 14452) that has been found in Rooibos (A. linearis) tea and has diverse biological activities.It reduces survival of Bel 7402 and HepG2 cancer cells when used at a concentration of 100 μM.Trilobatin increases superoxide dismutase (SOD) and glutathione peroxidase (GPX) activity (EC50s = 129 and 128 μM, respectively) and inhibits lipid peroxidation (IC50 = 88 μM) in rat liver homogenates.	price>

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