Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00366	Sanggenone C,cas:80651-76-9	Sanggenone C(C40H36O12,708.7) is a flavonoid that has been found in mulberry bark and has diverse biological activities.It inhibits TNF-α- or IL-1β-induced polymorphonuclear leukocyte (PMN) adhesion to human synovial cells (HSCs; IC50s = 27.29 and 54.43 nM, respectively), as well as inhibits NF-κB activation in HSCs.Sanggenone C induces apoptosis and production of reactive oxygen species (ROS) in HT-29 cells when used at concentrations ranging from 10 to 40 µM.	price>
R-XASYS-00367	Incensole Acetate,cas:34701-53-6	Incensole acetate(C22H36O3,348.5) is a diterpene originally isolated from frankincense produced by B. carterii that has diverse biological activities.It is an activator of transient receptor potential vanilloid 3 (TRPV3) that induces calcium influx in HEK293 cells expressing TRPV3 (EC50 = 16 µM).Incensole acetate (60-140 µM) inhibits degradation of inhibitor of NF-κB (IκBα) in TNF-α-stimulated HeLa cells.	price>
R-XASYS-00368	Ganoderic Acid A,cas:81907-62-2	Ganoderic acid A(C30H44O7,516.7) is a triterpene that has been found in Ganoderma and has diverse biological activities.It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells.Ganoderic acid A (2-100μg/ml) reduces hypoxia-induced apoptosis in H9c2 cardiomyocytes.	price>
R-XASYS-00369	Ginsenoside Ro,cas:34367-04-9	Ginsenoside Ro(C48H76O19,957.1) is a non-steroid glycoside that has been found in plants of the genus Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities.It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200μM.	price>
R-XASYS-00370	Schizandrin,cas:7432-28-2	Schizandrin(C24H32O7,432.5) is a dibenzocyclooctadiene lignan and a major component of S. chinensis and has diverse biological activities.It induces cell cycle arrest at the G0/G1 phase and inhibits growth of T47D and MDA-MB-231 breast cancer cells when used at a concentration of 100μM.	price>
R-XASYS-00371	10-Gingerol,cas:23513-15-7	10-Gingerol(C21H34O4,350.5) is a phenol that has been found in Z. officinale and has diverse biological activities.It scavenges DPPH, superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 µM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 µM.	price>
R-XASYS-00372	Sparstolonin B,cas:1259330-61-4	Sparstolonin B(C15H8O5,268.2) is an isocoumarin that has been found in Spaganium stoloniferum and has diverse biological activities.It inhibits increases in TNF-α, IL-6, and IL-1β levels induced by the toll-like receptor 4 (TLR4) agonist LPS, TLR2 agonist Pam3CSK4 , or TLR2/6 agonist FSL-1 but not the TLR3 agonist poly(I:C) or TLR9 agonist ODN1668 in primary mouse macrophages when used at a concentration of 100 µM.	price>
R-XASYS-00373	Dihydromyricetin,cas:27200-12-0	Dihydromyricetin(C15H12O8,320.3) is a natural flavanonol isolated from A. grossedentata, H. dulcis, and other plants that has antioxidant, antiproliferative, anti-apoptotic, and anti-alcohol intoxication properties.Dihydromyricetin scavenges 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals (IC50 = 0.235 μg/ml) and decreases reactive oxygen species (ROS) generated by AAPH in human erythrocytes when used at a concentration of 6 μg/ml.	price>
R-XASYS-00374	Streptochlorin,cas:120191-51-7	Streptochlorin(C11H7ClN2O,218.6) is a bacterial metabolite originally isolated from Streptomyces sp. SF2583 that has diverse biological activities, including antiangiogenic, antiproliferative, and anti-allergic properties.It inhibits TNF-α-induced NF-κB transcriptional activity and decreases proliferation of human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 20 µM.	price>
R-XASYS-00375	Phillyrin,cas:487-41-2	Phillyrin(C27H34O11,534.6) is a lignan that has been found in F. suspense and has diverse biological activities.It reduces hydrogen peroxide-induced caspase activation, increases in malondialdehyde (MDA) levels, and production of reactive oxygen species (ROS), as well as increases glutathione peroxidase (GPX) and superoxide dismutase (SOD) activities in PC12 cells.	price>

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