Product fluorescent-dyes-No-ROS-Rox-derivatives

Home > products > fluorescent-dyes> No-ROS-Rox-derivatives

Catalog	name	Description	price
R-XASYS-00326	Atractylenolide II,cas:73069-14-4	Atractylenolide II(C15H20O2,232.3) is a sesquiterpene that has been found in D. metel and has diverse biological activities.It inhibits proliferation of, as well as halts the cell cycle at the G2/M phase and induces apoptosis in, DU145 and LNCaP prostate cancer cells when used at concentrations of 50 and 100 µM.	price>
R-XASYS-00327	CFTR Inhibitor-172,cas:307510-92-5	The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR).CFTR inhibitor-172(C18H10F3NO3S2,409.4) is a thiazolidinone that selectively blocks the CFTR channel (Ki = 300 nM) in a voltage-independent manner.	price>
R-XASYS-00328	Ferrostatin-1,cas:347174-05-4	Ferrostatin-1(C15H22N2O2,262.4) is a ferroptosis inhibitor.It inhibits cell death induced by the ferroptosis inducers erastin (EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 μM.	price>
R-XASYS-00329	Levistolide A,cas:88182-33-6	Levistolide A(C24H28O4,380.5) is a phthalide that has been found in Angelica tenuissima and has diverse biological activities.It inhibits histamine release induced by phorbol 12-myristate 13-acetate (TPA) and A23187 from HMC-1 human mast cell leukemia cells when used at a concentration of 10 µM.	price>
R-XASYS-00330	LY345899,cas:10538-99-5	LY345899(C20H21N7O7,471.4) is an inhibitor of methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) and MTHFD2 (IC50s = 96 and 663 nM, respectively).It decreases the NADPH-to-NADP+ (NADPH/NADP+) and reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratios and increases the production of reactive oxygen species (ROS) in HCT116, SW620, and LoVo colorectal cancer cells when used at a concentration of 10 µM.	price>
R-XASYS-00331	6-Shogaol,cas:555-66-8	6-Shogaol(C17H24O3,276.4) is a minor, bioactive component of ginger (Zingiber officinale Roscoe) with anti-inflammatory and anticancer properties. It is present in fresh ginger at low levels, but quantities of 6-shogaol are significantly increased in dried ginger. 6-Shogaol induces apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase.	price>
R-XASYS-00332	(±)-Dunnione,cas:521-49-3	(±)-Dunnione(C15H14O3,242.3) is a naturally occurring naphthoquinone with diverse biological activities.It exhibits fungicidal activity against ten agriculturally relevant plant fungi in vitro (MICs = 5-20 mg/L) and in infected wheat and barley plants (EC50s = 2-20 mg/L).1 (±)-Dunnione also reduces the growth of T. cruzi epimastigotes (IC50 = 4.01 μM).	price>
R-XASYS-00333	Sciadopitysin,cas:521-34-6	Sciadopitysin(C33H24O10,580.5) is a biflavonoid originally isolated from G. biloba and has diverse biological activities.It reduces cytotoxicity induced by amyloid-β (1-42) (Aβ42) in PC12 cells (EC50 = 9.84 μM).2 Sciadopitysin (0.1-10 μM) decreases methylglyoxal-induced insulin secretion, production of reactive oxygen species (ROS)	price>
R-XASYS-00334	Pulchinenoside B4,cas:129741-57-7	Pulchinenoside B4(C59H96O26,1221.4) is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities.It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM.	price>
R-XASYS-00335	R162,cas:64302-87-0	R162(C17H12O3,264.3) is an inhibitor of glutamate dehydrogenase 1 (GDH1; IC50 = 23 µM). It decreases intracellular fumarate levels and increases the production of mitochondrial reactive oxygen species (ROS) in human H1299 lung and MDA-MB-231 breast cancer cells.	price>

...