Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00306	Terrecyclic Acid,cas:83058-94-0	Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.	price>
R-XASYS-00307	Daunorubicin (hydrochloride),cas:23541-50-6	Daunorubicin is an antitumor antibiotic.1 At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 acute myeloid leukemia (AML) cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations.	price>
R-XASYS-00308	Procyanidin B1,cas:20315-25-7	Procyanidin B1(C30H26O12,578.5) is a polyphenol flavonoid existing as a dimer of (+)-catechin and (−)-epicatechin. It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 µM.1 Procyanidin B1 (10 µg/ml)	price>
R-XASYS-00309	Sitamaquine (tosylate),cas:1019640-33-5	Sitamaquine(C21H33N3O•C7H8O3S,515.7) is an antileishmanial agent.It is active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica.It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 µM.	price>
R-XASYS-00310	Hypocrellin B,cas:123940-54-5	Hypocrellin B(C30H24O9,528.5) is a fungal metabolite that has been found in H. bambuase and has anticancer and antibacterial activities.It acts as a sonosensitizer, decreasing the viability of MDA-MB-231 breast cancer cells and inducing apoptosis in the presence of ultrasound exposure, effects that can be inhibited by the caspase inhibitor z-VAD-FMK.	price>
R-XASYS-00311	5-fluoro 203,cas:260443-89-8	5-fluoro 203(C14H11FN2S,258.3) is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK.	price>
R-XASYS-00312	α-Boswellic Acid,cas:471-66-9	α-Boswellic acid(C30H48O3,456.7) is a pentacyclic triterpene and an isomer of β-boswellic acid originally isolated from B. serrata.It increases Survivin and Reelin expression, decreases production of reactive oxygen species (ROS) and levels of hyperphosphorylated Tau	price>
R-XASYS-00313	Cytochalasin H,cas:53760-19-3	The cytochalasins(C30H39NO5,493.6) are cell-permeable fungal metabolites that inhibit actin polymerization.This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.	price>
R-XASYS-00314	Erythrodiol,cas:545-48-2	Erythrodiol(C30H50O2,442.7) is a triterpene that has been found in olive oil and has diverse biological activities.It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 µM).Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 µM).	price>
R-XASYS-00315	B355252,cas:1261576-81-1	B355252(C25H24ClN3O3S2,514.1) is a neuroprotective agent.It potentiates NGF-induced neurite outgrowth in NS-1 cells (EC50 = ~1 μM).B355252 inhibits glutamate-induced excitotoxicity in HT-22 cells in a concentration-dependent manner and inhibits glutamate-induced decreases in GSH levels and increases in Bax levels	price>

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