Catalog |
name |
Description |
price |
R-XASYS-00286 |
JX06,cas:729-46-4 |
JX06(C10H16N2O2S4,324.5) is an irreversible inhibitor of pyruvate dehydrogenase kinases (PDHKs; IC50s = 49, 101, and 313 nM for PDHK1, PDHK2, and PDHK3, respectively).It is selective for PDHK1-3 over PDHK4 (IC50 = >10 µM) and 322 other kinases at 10 µM but does inhibit FAK in a cell-free panel but not in a cell-based assay. |
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R-XASYS-00287 |
Isosilybin,cas:72581-71-6 |
Isosilybin(C25H22O10,482.4) is a flavanolignan found in the extract of S. marianum fruits with antioxidant and anticancer activities.It inhibits lipid peroxidation in rat liver microsomes (IC50 = 32 μM) and reduces ADP/Fe3+-induced malondialdehyde (MDA) production and lactate dehydrogenase (LDH) release in rat hepatocytes. |
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R-XASYS-00288 |
Ginsenoside Rb3,cas:68406-26-8 |
Ginsenoside Rb3(C53H90O22,1079.3) is a steroid glycoside that has been found in Panax and has diverse biological activities.It inhibits JNK-mediated activation of NF-κB and apoptosis induced by oxygen-glucose deprivation (OGD) in H9c2 mouse cardiac myoblasts in vitro and reduces myocardial apoptosis |
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R-XASYS-00289 |
Theaflavin,cas:4670-05-7 |
Theaflavin(C29H24O12,564.5) is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral properties.It scavenges singlet oxygen and hydrogen peroxide as well as superoxide and hydroxide radicals in vitro (IC50s = 0.73, 0.49, 14.5, and 38.0 µM. |
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R-XASYS-00290 |
Coptisine (chloride),cas:6020-18-4 |
Coptisine(C19H14NO4•Cl,355.8) is an isoquinoline alkaloid that has been found in Coptis chinensis and has diverse biological activities, including antioxidant, enzyme inhibitory, antiproliferative, and anti‑hypercholesterolemic properties. |
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R-XASYS-00291 |
MGR2,cas:2361529-47-5 |
MGR2(C16H18O3,258.3) is a negative control compound for the activity of the reactive oxygen species-generating probe MGR1 |
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R-XASYS-00292 |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC,cas:1872379-72-0 |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC(C24H41D9NO7P,504.7) is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PC by GC- or LC-MS. |
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R-XASYS-00293 |
Isosakuranetin,cas:480-43-3 |
Isosakuranetin(C16H14O5,286.3) is a flavanone that has been found in Citrus species and has diverse biological activities.It inhibits calcium uptake induced by pregnenolone sulfate (PregS) in HEK293 cells expressing mouse transient receptor potential melastatin. |
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R-XASYS-00294 |
Macranthoidin B,cas:136849-88-2 |
Macranthoidin B(C65H106O32,1399.5) is a triterpenoid saponin that has been found in Lonicerae and has anticancer activity.It increases the production of reactive oxygen species (ROS) and induces apoptosis in HCT116 cells when used at concentrations ranging from 20 to 400 µM |
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R-XASYS-00295 |
Chebulagic Acid,cas:23094-71-5 |
Chebulagic acid(C41H30O27,954.7) is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities.1,2,3,4,5 It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). |
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