Catalog |
name |
Description |
price |
R-XASYS-00266 |
Luteoloside,cas:5373-11-5 |
Luteoloside(C21H20O11,448.4) is a flavonoid that has been found in many Chinese herbs with diverse biological activities.It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. |
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R-XASYS-00267 |
Gomisin C,cas:58546-56-8 |
Gomisin C(C30H32O9,536.6), a lignan first isolated from the fruits of S. chinensis, scavenges oxygen radicals and reduces the production of reactive oxygen species by inhibiting neutrophil activity.It has been shown to attenuate respiratory burst in rat peripheral neutrophils via suppression of NADPH oxidase (39% inhibition at 30 µg/ml) and inhibition of cytosolic calcium release from intracellular stores (36% inhibition at 50 µg/ml). |
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R-XASYS-00268 |
Senkyunolide H,cas:94596-27-7 |
Senkyunolide H(C12H16O4,224.3) is a phthalide that has been found in L. chuanxiong and has diverse biological activities.It increases levels of heme oxygenase-1 (HO-1) in HepG2 cells, as well as reduces hydrogen peroxide-induced increases in reactive oxygen species (ROS) and malondialdehyde (MDA) in the same cells when used at concentrations of 150 and 200 µg/ml. |
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R-XASYS-00269 |
Rhamnetin,cas:90-19-7 |
Rhamnetin(C16H12O7,316.3) is a flavonoid that has been found in O. falcate and has diverse biological activities.It reduces production of reactive oxygen species (ROS) and apoptosis induced by miconazole (Item No. 15420) in H9c2 cardiomyocytes. |
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R-XASYS-00270 |
NADPH (cyclohexyl ammonium salt),cas:100929-71-3 |
NADPH(C21H30N7O17P3•4C6H13N,1142.1) is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. |
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R-XASYS-00271 |
Alantolactone,cas:546-43-0 |
Alantolactone is a sesquiterpene lactone that has been found in Inula species and has diverse biological activities.It inhibits LPS-induced increases in nitric oxide, IL-6, and TNF-α production in RAW 246.7 cells by 76.09, 81.54, and 71.23%, respectively, when used at a concentration of 10 μM. |
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R-XASYS-00272 |
Procyanidin C1,cas:37064-30-5 |
Procyanidin(C45H38O18,866.8) C1 is a polyphenol flavonoid trimer of (–)-epicatechin that has HIV-related and antioxidant activities.It activates latent HIV-1 provirus in JLR2 cells when used at concentrations ranging from 12.5 to 50 µM and increases NF-κB-dependent transcriptional activity in Jurkat T cells. |
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R-XASYS-00273 |
6-OHDA (hydrobromide),cas:636-00-0 |
6-OHDA(C8H11NO3•HBr,250.1) is a catecholaminergic neurotoxin that has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinsons disease in rodents.It induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, medial forebrain bundle (MFB), or striatum at doses of 9, 6, and 18 μg. |
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R-XASYS-00274 |
Antimycin A3,cas:522-70-3 |
Antimycin A3(C26H36N2O9,520.6) is a component of the antimycin A antibiotic complex that is more polar than antimycin A1 and antimycin A2 but not antimycin A4.Antimycin A3 binds to the Q(inner) site of mitochondrial complex III (cytochrome bc1) and inhibits mitochondrial respiration (IC50 = 38 nM in isolated rat liver mitochondria). |
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R-XASYS-00275 |
Disulfiram-d20,cas:1216403-88-1 |
Disulfiram-d20(C10D20N2S4,316.7) is intended for use as an internal standard for the quantification of disulfiram by GC- or LC-MS. Disulfiram is a copper and zinc chelator and an irreversible inhibitor of aldehyde dehydrogenase (IC50 = 0.1 mM).It also inhibits the copper-dependent enzyme dopamine β-hydroxylase, which prevents the breakdown of dopamine. |
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