Product fluorescent-dyes-No-ROS-Rox-derivatives

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Catalog	name	Description	price
R-XASYS-00256	QD-394,cas:2132411-21-1	QD-394(C19H19N5O2,349.4) is an inducer of reactive oxygen species (ROS) production.It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to oxidized GSH (GSSG) ratio in MIA PaCa-2 pancreatic cancer cells.	price>
R-XASYS-00257	6-Formylpterin,cas:712-30-1	6-Formylpterin(C7H5N5O2,191.1) is an oxidized pterin produced by photolytic breakdown of folic acid.It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site.	price>
R-XASYS-00258	7-Azido-4-methylcoumarin,cas:95633-27-5	7-Azido-4-methylcoumarin (AzMC)(C10H7N3O2,201.2) is a coumarin fluorescent probe for hydrogen sulfide (H2S).AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species.	price>
R-XASYS-00259	LysoFP-NO2,cas:69408-75-9	LysoFP-NO2(C18H17N3O5,355.3) is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome.In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent.	price>
R-XASYS-00260	Jacaric Acid,cas:28872-28-8	Jacaric acid(C18H30O2,278.4) is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants.Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid. Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 µM).	price>
R-XASYS-00261	8-Hydroxy-2-deoxyguanosine,cas:88847-89-6	8-Hydroxy-2-deoxyguanosine(C10H13N5O5,283.2) is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.	price>
R-XASYS-00262	Isoquercetin,cas:482-35-9	Isoquercetin(C21H20O12,464.4) is a flavonoid that has been isolated from A. venetum and has diverse biological activities, including antiviral, anti-apoptotic, and neuroprotective properties.It reduces viral titers of H5N1 influenza isolates by 79.66% in a plaque assay when used at a concentration of 1 ng/ml.	price>
R-XASYS-00263	MitoTEMPO (hydrate),cas:1569257-94-8	MitoTEMPO(C29H35N2O2P•Cl [H2O],528.0) is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium.	price>
R-XASYS-00264	4-amino-1,8-Naphthalimide,cas:1742-95-6	4-amino-1,8-Naphthalimide (4-ANI)(C12H8N2O2,212.2) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.4-ANI is used to study the role of PARP activity in various cell systems.	price>
R-XASYS-00265	Aldehyde Reactive Probe (trifluoroacetate salt),cas:627090-10-2	DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA.	price>

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