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(S,R,S)-AHPC-Me hydrochloride

(S,R,S)-AHPC-Me hydrochloride

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R-R-0345 1g 160.00
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Product description

(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.

(S,R,S)-AHPC-Me hydrochloride

Appearance N/A
Molecular Weight 481.05
Purity >90%
CAS 1948273-03-7
Formula C23H33ClN4O3S
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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