Product apis-stem-cells-wwnt

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Catalog	name	Description	price
R-C-1918	SKL 2001 CAS:909089-13-0	SKL2001 is an agonist of the Wnt/β-catenin pathway,with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.	price>
R-C-1936	GIGANTOL CAS:67884-30-4	Gigantol is a bibenzyl compound derived from several medicinal orchids.Giganto shows promising therapeutic potential against cancer cells.Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.	price>
R-C-1947	IMR-1 CAS:310456-65-6	IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with an IC50 of 26μM.IMR-1 prevents the recruitment of Mastermind-like 1(Maml1)to the Notch Ternary Complex(NTC)on chromatin,inhibits Notch target gene transcription and dramatically inhibits tumor growth.	price>
R-C-2134	Ac-COA Synthase Inhibitor CAS：508186-14-9	Ac-CoA Synthase Inhibitor1 is a potent,reversible acetate-dependent acetyl-CoA synthetase 2(ACSS2)inhibitor with an IC50 of 0.6µM.Ac-CoA Synthase Inhibitor1 inhibits the respiratory syncytial virus(RSV).	price>
R-C-2508	PF-5274857 CAS:1373615-35-0	PF-5274857 is a potent,selective,orally active and brain-penetrant antagonist of Smo,with an IC50 of 5.8nM and Ki of 4.6nM. PF-5274857 has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.	price>
R-C-2558	BML-284 CAS:853220-52-7	BML-284 is a potent and cell-permeable Wnt signaling activator.BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700nM.	price>
R-C-2663	XAV-939 CAS:284028-89-3	XAV-939 is a potent tankyrase inhibitor that targets Wnt/β-catenin signaling.XAV-939 stabilizes axin by inhibiting tankyrase 1 and tankyrase 2(IC50s of 5 and 2nM,respectively),thereby stimulating β-catenin degradation.XAV939 binds tightly to the catalytic(PARP)domains of TNKS1 and TNKS2(Kds of 99 and 93nM,respectively).	price>
R-R-4672	JPH203 CAS No:1037592-40-7	JPH203 (KYT-0353, JPH-203SBECD) is a selective L-type amino acid transporter 1 inhibitor.	price>
R-C-3265	U18666A CAS：3039-71-2	U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3266	TAK-441 CAS：1186231-83-3	TAK-441 is a pyrrolo[3,2-c]pyridine derivative,as a highly potent and orally active hedgehog signaling inhibitor.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>

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