Product apis-stem-cells-wwnt

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Catalog	name	Description	price
R-C-3269	ETC-159 CAS：1638250-96-0	ETC-159 is a potent and specific inhibitor of Wnt secretion.ETC-159 inhibits beta-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9nM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3271	CCT251545 CAS:1661839-45-7	CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with an IC50 of 5 nM in 7dF3 cells.CCT251545 is a selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3364	JW74 CAS:863405-60-1	JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.The product is only suitable for scientific research and test, not for clinical experiment and human body.	price>
R-C-3365	ICG-001 CAS:780757-88-2	ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3366	IWP-2 CAS:686770-61-6	IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production,and blocks beta-catenin accumulation.Wnt/b-catenin (canonical) pathway maintains transcriptional programs that enable stem cells to remain multipotent.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3367	KYA1797K CAS:1956356-56-1	KYA1797K is a highly potent and selective Wnt/beta-catenin inhibitor with IC50 of 0.75 μM (TOPflash assay).Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3368	Longdaysin CAS:1353867-91-0	Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling.Longdaysin inhibits CK1α,CK1δ,CDK7,and ERK2 with IC50s of 5.6µM,8.µM,29µM,and 52µM, respectively.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3369	WAY-316606 CAS:915759-45-4	WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3371	PF 670462 CAS:950912-80-8	Potent and selective casein kinase 1ε (CK1ε)and CK1δ inhibitor(IC50 values are 7.7 and 14nM respectively)that displays>30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation(EC50=290nM)causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3372	BMS-708163 (Avagacestat) CAS:1146699-66-2	Avagacestat(BMS-708163)is a potent,selective,orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3nM and 0.27nM,demonstrating a 193-fold selectivity against Notch. Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>

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