JPH203 CAS No:1037592-40-7

JPH203/O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine/CAS No:1037592-40-7 is a compound that has been shown to inhibit the growth of hypoxic tumor cells. It was found to induce apoptosis in tubule cells through a number of mechanisms, including the inhibition of cyclin D2 protein synthesis and the disruption of cellular signaling pathways. JPH203 is structurally similar to organic anion transporters (OATs), which are drug transporters in the body. This property may help it to cross the blood-brain barrier and reach tumors in the brain. JPH203 has also been shown to inhibit cancer cell proliferation and induce apoptosis in colorectal adenocarcinoma cells, as well as inhibiting tumor growth in animal models.

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