Product apis-pi3k-akt-mtor

Home > products > apis> pi3k-akt-mtor

Catalog	name	Description	price
R-C-3042	PIK-90 CAS：677338-12-4	PIK-90 is a PI3Kα/γ/δ inhibitor with IC50 of 11 nM/18 nM/58 nM, respectively, less potent to PI3Kβ.	price>
R-C-3043	TG100-115 CAS：677297-51-7	TG100-115, inhibited PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively), whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μM). As a gauge of general specificity, TG100-115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values <1 μM.	price>
R-C-3044	ZSTK474 CAS：475110-96-4	ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.	price>
R-C-3045	PIK-75 CAS：372196-77-5	PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.	price>
R-C-3046	MTI-31 CAS：1567915-38-1	MTI-31 (LXI-15029) is a novel mTORC1/mTORC2 inhibitor with Kd of 0.2 nM in mTOR binding assays and displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.	price>
R-C-3047	mTOR inhibitor-1 cas:468747-17-3	mTOR inhibitor-1 is a novel inhibitor of mTOR pathway. mTOR inhibitor-1 suppress cells proliferation and induces autophagy.	price>
R-C-3048	LY303511 hydrochloride cas:2070014-90-1	LY303511 hydrochloride is a structural analogue of LY294002. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. LY303511 does not inhibit PI3K.	price>
R-C-3049	GNE-477 CAS:1032754-81-6	GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR.	price>
R-C-3050	LY 303511 CAS:154447-38-8	LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.	price>
R-C-3051	WYE-125132 (WYE-132) CAS:1144068-46-1	WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).	price>

...