Catalog |
name |
Description |
price |
R-C-2996 |
740 Y-P cas:1236188-16-1 |
740 Y-P is a potent and cell permeable PI3K activator.Only for scientific research, not for human body. |
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R-C-3025 |
PF-4989216 CAS:1276553-09-3 |
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Only for scientific research, not for human body. |
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R-C-3026 |
AZD8835 cas:1620576-64-8 |
AZD8835 is a potent inhibitor of PI3Kα (wild type, E545K and H1047R mutations) and PI3Kδ with excellent selectivity vs. PI3Kβ, PI3Kγ and an excellent general kinase selectivity.Only for scientific research, not for human body. |
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R-C-3027 |
TGR-1202 (Umbralisib) CAS:1532533-67-7 |
Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.Only for scientific research, not for human body. |
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R-C-3028 |
GDC-0326 CAS:1282514-88-8 |
GDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.Only for scientific research, not for human body. |
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R-C-3029 |
acalisib (GS-9820) CAS:870281-34-8 |
Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.Only for scientific research, not for human body. |
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R-C-3031 |
AMG 511 CAS:1253573-53-3 |
AMG 511 is a potent and selective pan class I PI3K inhibitor, capable of inhibiting PI3K signaling and inducing robust anti-proliferative effects via a G1 arrest in many tumor cell lines, with evidence of cell killing in a subset of lines.Only for scientific research, not for human body. |
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R-C-3032 |
AS-604850 CAS:648449-76-7 |
AS-604850 is a selective,ATP-competitive PI3Kγ inhibitor with IC50 of 250nM,over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα.Only for scientific research, not for human body. |
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R-C-3040 |
Duvelisib (IPI-145) CAS:1201438-56-3 |
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. |
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R-C-3041 |
GSK1059615 CAS:958852-01-2 |
GSK1059615 is a potent, ATP-competitive inhibitor of PI 3-kinase alpha (PI3Kα) with IC50 of 2 nM. GSK1059615 is also a novel inhibitor of PI3Kβ, PI3Kδ, PI3Kγ and mTOR with IC50 of 0.6 nM, 2 nM, 5 nM and 12 nM, respectively. |
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