Product apis-pi3k-akt-mtor

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Catalog	name	Description	price
R-C-1874	IPI3063 CAS:1425043-73-7	IPI-3063 is a Selective Phosphoinoside-3-Kinase p110δInhibitor.IPI-3063 Potently Suppresses B Cell Survival,Proliferation,and Differentiation.IPI-3063 is a highly potent molecule useful for studying p110δ function in immune cells.	price>
R-C-2256	Homosalate CAS：118-56-9	Homosalat(HMS,Homomenthyl salicylate)is an organic ultraviolet filter used in most sunscreens but has been reported to be toxic to marine organisms. Homosalate aggravates the invasion of human trophoblast cells as well as regulates intracellular signaling pathways including PI3K/AKT and MAPK pathways.	price>
R-C-2259	Methyl-Hesperidin CAS：11013-97-1	Methyl Hesperidin is a flavanone glycoside(flavonoid)(C28H34O15)found abundantly in citrus fruits.Its aglycone form is called hesperetin.	price>
R-C-1901	SF 2523 CAS：1174428-47-7	SF2523 is a highly selective and potent inhibitor of PI3K with IC50 values of 34 nM,158nM,9nM,241nM and 280nM for PI3Kα,PI3Kγ,DNA-PK,BRD4 and mTOR, respectively.	price>
R-C-1934	BAY 80-6946 CAS:1032568-63-0	Copanlisib(BAY80-6946)is a potent,selective and ATP-competitive pan-class I PI3K inhibitor,with IC50s of 0.5nM,0.7nM,3.7nM and 6.4nM for PI3Kα,PI3Kδ,PI3Kβ and PI3Kγ,respectively.Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases,except for mTOR. Copanlisib has superior antitumor activity.	price>
R-C-1975	AZD8186 CAS：1627494-13-6	AZD8186 is a PI3K inhibitor,which potently inhibits PI3Kβ(IC50=4 nM)and PI3Kδ(IC5050=12nM)with selectivity over PI3Kα(IC50=35nM)and PI3Kγ(IC50=675 nM).	price>
R-C-1976	Bimiralisib (PQR309) CAS;1225037-39-7	Bimiralisib(PQR309)is a potent,brain-penetrant,orally bioavailable,pan-class I PI3K/mTOR inhibitor with IC50s of 33nM,451nM,661nM,708nM and 89nM for PI3Kα,PI3Kδ,PI3Kβ,PI3Kγ and mTOR,respectively.Bimiralisib is an mTORC1 and mTORC2 inhibitor.	price>
R-C-1983	leniolisib(CDZ 173) CAS：1354690-24-6	Leniolisib(CDZ173)is a potent and selective PI3Kδ inhibitor.Leniolisib has the potential for immunodeficiency disorders treatment.	price>
R-C-3021	Serabelisib (MLN1117, INK1117, TAK-117) CAS# 1268454-23-4	PI3K alpha inhibitor INK1117 selectively inhibits PI3K alpha kinase, including mutations of PIK3CA, in the PI3K/Akt/mTOR pathway,which may result in tumor cell apoptosis and growth inhibition in PI3K alpha-expressing tumor cells. Only for scientific research, not for human body.	price>
R-C-3022	VPS34-IN1 CAS：1383716-33-3	Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks. Vps34-IN1 modulates autophagy.Only for scientific research, not for human body.	price>

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